Barley is more sensitive than the other major cereal crops to aluminium (Al) toxicity. Here, a doubled haploid mapping population was exploited to study the inheritance of Al tolerance in barley. Quantitative trait locus (QTL) mapping was based on a genetic map constructed with genic markers. Al tolerance QTL were identified on chromosomes 2H, 3H and 4H. A sequence homology search was used to derive the putative function of the genes linked to the QTL, in order to identify potential candidate genes for Al tolerance. Some of these candidates are implicated in stress/defence responses, in particular, stress signal transduction, transcription regulation factors and cell metabolism.
Aniol, A., Gustafson, J.P. 1984. Chromosome location of genes controlling aluminium tolerance in wheat, rye and triticale. Can. J. Genet. Cytol. 26 :701–705.
Gustafson J.P. , 'Chromosome location of genes controlling aluminium tolerance in wheat, rye and triticale ' (1984 ) 26 Can. J. Genet. Cytol. : 701 -705.
Bona, L., Wright, R.J., Baligar, V.C., Matuz, J. 1993. Screening wheat and other small grains for acid soil tolerance. Landscape and Urban Planning 27 :2–4, 175–178.
Matuz J. , 'Screening wheat and other small grains for acid soil tolerance ' (1993 ) 27 Landscape and Urban Planning : 175 -178.
Cai, S., Bai, G-H., Zhang, D. 2008. Quantitative trait loci for aluminum resistance in Chinese wheat landrace FSW. Theor. Appl. Genet. 117 :49–56.
Zhang D. , 'Quantitative trait loci for aluminum resistance in Chinese wheat landrace FSW ' (2008 ) 117 Theor. Appl. Genet. : 49 -56.
Collins, N.C., Shirley, N.J., Saeed, M., Pallotta, M., Gustafson, J.P. 2008. An ALMT1 gene cluster controlling aluminum tolerance at the Alt4 locus of rye ( Secale cereale L.). Genetics 179 :669–682.
Gustafson J.P. , 'An ALMT1 gene cluster controlling aluminum tolerance at the Alt4 locus of rye (Secale cereale L.) ' (2008 ) 179 Genetics : 669 -682.
Costa, J.M., Corey, A., Hayes, P.M., Jobet, C., Kleinhofs, A., Kopisch-Obusch, A., Kramer, S.F., Kudrna, D., Li, M., Riera-Lizarazu, O., Sato, K., Szucs, P., Toojinda, T., Vales, M.I., Wolfe, R.I. 2001. Molecular mapping of the Oregon Wolfe Barleys: A phenotypically polymorphic doubled-haploid population. Theor. Appl. Genet. 103 :415–424.
Wolfe R.I. , 'Molecular mapping of the Oregon Wolfe Barleys: A phenotypically polymorphic doubled-haploid population ' (2001 ) 103 Theor. Appl. Genet. : 415 -424.
Delhaize, E., Ryan, P.R. 1995. Aluminum toxicity and tolerance in plants. Plant Physiol. 107 :315–321.
Ryan P.R. , 'Aluminum toxicity and tolerance in plants ' (1995 ) 107 Plant Physiol. : 315 -321.
Echart, C.L., Fernandes Barbosa-Neto, J., Garvin, D.F., Cavalli-Molina, S. 2002. Aluminum tolerance in barley: Methods for screening and genetic analysis. Euphytica 126 :309–313.
Cavalli-Molina S. , 'Aluminum tolerance in barley: Methods for screening and genetic analysis ' (2002 ) 126 Euphytica : 309 -313.
Fontecha, G., Silva-Navas, J., Benito, C., Mestres, M.A., Espino, F.J., Hernandez-Riquer, M.V., Gallego, F.J. 2007. Candidate gene identification of an aluminum-activated organic acid transporter gene at the Alt4 locusfor aluminum tolerance in rye ( Secale cereale L.). Theor. Appl. Genet. 114 :249–260.
Gallego F.J. , 'Candidate gene identification of an aluminum-activated organic acid transporter gene at the Alt4 locusfor aluminum tolerance in rye (Secale cereale L.) ' (2007 ) 114 Theor. Appl. Genet. : 249 -260.
Furukawa, J., Yamaji, N., Wang, H., Mitani, N., Murata, Y., Sato, K., Katsuhara, M., Takeda, K., Ma, J.F. 2007. An aluminum-activated citrate transporter in barley. Plant and Cell Physiol. 48 :1081–1091.
Ma J.F. , 'An aluminum-activated citrate transporter in barley ' (2007 ) 48 Plant and Cell Physiol : 1081 -1091.
Gallego, F.J., Benito, C. 1997. Genetic control of aluminium tolerance in rye ( Secale cereale L.). Theor. Appl. Genet. 95 :393–399.
Benito C. , 'Genetic control of aluminium tolerance in rye (Secale cereale L.) ' (1997 ) 95 Theor. Appl. Genet. : 393 -399.
Gruber, B.D., Ryan, P.R., Richardson, A.E., Hebb, D.M., Raman, H., Zhou, M., Wang, J., Howitt, S.M., Delhaize, E. 2006. The identification and characterisation of ALMT1 homologs in the Triticeae . In: Proceedingsof 8 th international congress of plant molecular biology. Adelaide, Australia, p. 185.
Hede, A.R., Skovmand, B., Ribaut, J.M., Gonzalez-de-Leon, D., Stolen, O. 2002. Evaluation of aluminium tolerance in a spring rye collection by hydroponic screening. Plant Breed. 121 :241–248.
Stolen O. , 'Evaluation of aluminium tolerance in a spring rye collection by hydroponic screening ' (2002 ) 121 Plant Breed. : 241 -248.
Hoekenga, O.A., Maron, L.G., Pineros, M.A., Cancado, G.M.A., Shaff, J., Kobayashi, Y., Ryan, P.R., Dong, B., Delhaize, E., Sasaki, T., Matsumoto, H., Yamamoto, Y., Koyama, H., Kochian, L.V. 2006. AtALMT1 , which encodes a malate transporter, is identified as one of several genes critical for aluminum tolerance in Arabidopsis. Proc. Natl. Acad. Sci. USA 103 : 9738–9743.
Kochian L.V. , 'AtALMT1, which encodes a malate transporter, is identified as one of several genes critical for aluminum tolerance in Arabidopsis ' (2006 ) 103 Proc. Natl. Acad. Sci. USA : 9738 -9743.
Ishikawa, S., Wagamatsu, T., Sasaki, R., Manu, P.O. 2000. Comparison of the amounts of citric and malic acids in Al media of seven plant species and two cultivars each in five plant species. Soil Sci. Plant Nutr. 46 :751–758.
Manu P.O. , 'Comparison of the amounts of citric and malic acids in Al media of seven plant species and two cultivars each in five plant species ' (2000 ) 46 Soil Sci. Plant Nutr. : 751 -758.
Iuchi, S., Koyama, H., Iuchi, A., Kobayashi, Y., Kitabayashi, S., Kobayashi, Y., Ikka, T., Hirayama, T., Shinozaki, K., Kobayashi, M. 2007. Zinc finger protein STOP1 is critical for proton tolerance in Arabidopsis and coregulates a key gene in aluminum tolerance. Proc. Natl. Acad. Sci. USA 104 :9900–9905.
Kobayashi M. , 'Zinc finger protein STOP1 is critical for proton tolerance in Arabidopsis and coregulates a key gene in aluminum tolerance ' (2007 ) 104 Proc. Natl. Acad. Sci. USA : 9900 -9905.
Kochian, L.V., Pineros, M.A., Hoekenga, O.A. 2005. The physiology, genetics and molecular biology of plant aluminum resistance and toxicity. Plant and Soil 274 :175–195.
Hoekenga O.A. , 'The physiology, genetics and molecular biology of plant aluminum resistance and toxicity ' (2005 ) 274 Plant and Soil : 175 -195.
Lefebvre, S., Lawson, T., Zakhleniuk, O.V., Lloyd, J.C., Raines, C.A. 2005. Increased sedoheptulose-1,7-bisphosphatase activity in transgenic tobacco plants stimulates photosynthesis and growth from an early stage in development. Plant Physiol. 138 :451–460.
Raines C.A. , 'Increased sedoheptulose-1,7-bisphosphatase activity in transgenic tobacco plants stimulates photosynthesis and growth from an early stage in development ' (2005 ) 138 Plant Physiol : 451 -460.
Ma, H-X., Bai, G-H., Lu, W-Z. 2006. Quantitative trait loci for aluminum resistance in wheat cultivar Chinese Spring. Plant and Soil 283 :239–249.
Lu W.-Z. , 'Quantitative trait loci for aluminum resistance in wheat cultivar Chinese Spring ' (2006 ) 283 Plant and Soil : 239 -249.
Ma, J.F., Nagao, S., Sato, K., Ito, H., Furukawa, J., Tekeda, K. 2004. Molecular mapping of a gene responsible for Al-activated secretion of citrate in barley. J. Exp. Bot. 55 :401, 1335–1341.
Tekeda K. , 'Molecular mapping of a gene responsible for Al-activated secretion of citrate in barley ' (2004 ) 55 J. Exp. Bot. : 1335 -1341.
Magalhaes, J.V., Liu, J., Guimaraes, C.T., Lana, U.G.P., Alves, V.M.C., Wang, Y.H., Schaffert, R.E., Hoekenga, O.A., Pineros, M.A., Shaff, J.E., Klein, P.E., Carneiro, N.P., Coelho, C.M., Trick, H.N., Kochian, L.V. 2007. A gene in the multidrug and toxic compound extrusion (MATE) family confers aluminum tolerance in sorghum. Nat. Genet. 39 :1156–1161.
Kochian L.V. , 'A gene in the multidrug and toxic compound extrusion (MATE) family confers aluminum tolerance in sorghum ' (2007 ) 39 Nat. Genet. : 1156 -1161.
Maron, L.G., Kirst, M., Mao, C., Milner, M.J., Menossi, M., Kochian, L.V. 2008. Transcriptional profiling of aluminum toxicity and tolerance responses in maize roots. New Phytol. 179 :116–128.
Kochian L.V. , 'Transcriptional profiling of aluminum toxicity and tolerance responses in maize roots ' (2008 ) 179 New Phytol. : 116 -128.
Minella, E., Sorrells, M.E. 1992. Aluminum tolerance in barley — genetic-relationships among genotypes of diverse origin. Crop Sci. 2 :593–598.
Sorrells M.E. , 'Aluminum tolerance in barley — genetic-relationships among genotypes of diverse origin ' (1992 ) 2 Crop Sci. : 593 -598.
Minella, E., Sorrells, M.E. 1997. Inheritance and chromosome location of Alp, a gene controlling aluminum tolerance in ‘Dayton’ barley. Plant Breed. 116 :465–469.
Sorrells M.E. , 'Inheritance and chromosome location of Alp, a gene controlling aluminum tolerance in ‘Dayton’ barley ' (1997 ) 116 Plant Breed. : 465 -469.
Navakode, S., Weidner, A., Lohwasser, U., Röder, M.S., Börner, A. 2009. Molecular mapping of quantitative trait loci (QTLs) controlling aluminium tolerance in bread wheat. Euphytica 166 :283–290.
Börner A. , 'Molecular mapping of quantitative trait loci (QTLs) controlling aluminium tolerance in bread wheat ' (2009 ) 166 Euphytica : 283 -290.
Nawrot, M., Szarejko, I., Maluszynski, M. 2001. Barley mutants with increased tolerance to aluminium toxicity. Euphytica 120 :345–356.
Maluszynski M. , 'Barley mutants with increased tolerance to aluminium toxicity ' (2001 ) 120 Euphytica : 345 -356.
Nelson, J.C. 1997. QGENE: Software for marker-based genomic analysis and breeding. Mol. Breed. 3 :239–245.
Nelson J.C. , 'QGENE: Software for marker-based genomic analysis and breeding ' (1997 ) 3 Mol. Breed. : 239 -245.
Nguyen, V.T., Nguyen, B.D., Sarkarung, S., Martinez, C., Paterson, A.H., Nguyen, H.T. 2002. Mapping of genes controlling aluminum tolerance in rice: comparison of different genetic backgrounds. Mol. Genet. Genomics267:772–780.
Nguyen H.T. , 'Mapping of genes controlling aluminum tolerance in rice: comparison of different genetic backgrounds ' (2002 ) 267 Mol. Genet. : 772 -780.
Oram, R.N. 1983. Breeding barley tolerant to high soil acidity and waterlogging. In: Driscoll, C.J. (Ed.), Proc. Aust. Plant breed. Conf. Adelaide, South Australia, pp. 71–73.
Peixoto, P.H.P., Cambrain, J., Anna, R.S., Mosquim, P.R., Moreira, M.A. 1999. Aluminium effects on lipid peroxidation and on the activities of enzymes of oxidative metabolism in sorghum. Br. J. Plant Physiol. 11 :137–145.
Moreira M.A. , 'Aluminium effects on lipid peroxidation and on the activities of enzymes of oxidative metabolism in sorghum ' (1999 ) 11 Br. J. Plant Physiol. : 137 -145.
Raman, H., Moroni, S., Sato, K., Read, J., Scott, J. 2002. Identification of AFLP and microsatellite markers linked with an aluminium tolerance gene in barley ( Hordeum vulgare L.). Theor. Appl. Genet. 105 :458–464.
Scott J. , 'Identification of AFLP and microsatellite markers linked with an aluminium tolerance gene in barley (Hordeum vulgare L.) ' (2002 ) 105 Theor. Appl. Genet. : 458 -464.
Raman, H., Wang, J.P., Read, B., Zhou, M.X., Vengatanagappa, S., Moroni, J.S., O’Bree, B., Mendham, N. 2005. Molecular mapping of resistance to aluminium toxicity in barley. In: Proceedings of Plant and Animal Genome XIII Conference, January 15–19, San Diego, p. 154.
Read, B.J., Oram, R.N. 1995. Hordeum vulgare (Barley) cv. Brindabella. Aust. J. Exp. Agric. 35 :425.
Oram R.N. , 'Hordeum vulgare (Barley) cv. Brindabella ' (1995 ) 35 Aust. J. Exp. Agric. : 425 -.
Reid, D.A. 1970. Genetic control of reaction to aluminum in winter barley. In: Proceedings of the 2 nd International Barley Genetics Symposium, Pullman, pp. 409–413.
Reid, D.A., Jones, G.D., Armiger, W.H., Foy, C.D., Koch, E.J., Starling, T.M. 1969. Differential aluminum tolerance of winter barley varieties and selections in associated greenhouse and field experiments. Agron. J. 161 :218–222.
Starling T.M. , 'Differential aluminum tolerance of winter barley varieties and selections in associated greenhouse and field experiments ' (1969 ) 161 Agron. J. : 218 -222.
Richards, K.D., Schott, E.J., Sharma, Y.K., Davis, K.R., Gardner, R.C. 1998. Aluminum induces oxidative stress genes in Arabidopsis thaliana . Plant Physiol. 116 :409–418.
Gardner R.C. , 'Aluminum induces oxidative stress genes in Arabidopsis thaliana ' (1998 ) 116 Plant Physiol. : 409 -418.
Ryan, P.R., Raman, H., Gupta, S., Horst, W.J., Delhaize, E. 2009. A second mechanism for aluminum resistance in wheat relies on the constitutive efflux of citrate from roots. Plant Physiol. 149 :340–351.
Delhaize E. , 'A second mechanism for aluminum resistance in wheat relies on the constitutive efflux of citrate from roots ' (2009 ) 149 Plant Physiol. : 340 -351.
Sasaki, T., Yamamoto, Y., Ezaki, B., Katsuhara, M., Ahn, S.J., Ryan, P.R., Delhaize, E., Matsumoto, H. 2004. A wheat gene encoding an aluminum-activated malate transporter. Plant Journal 37 :645–653.
Matsumoto H. , 'A wheat gene encoding an aluminum-activated malate transporter ' (2004 ) 37 Plant Journal : 645 -653.
Sibov, S.T., Gaspar, M., Silva, M.J., Ottoboni, L.M.M., Arruda, P., Souza, A.P. 1999. Two genes control aluminum tolerance in maize: Genetic and molecular mapping analyses. Genome 42 :475–482.
Souza A.P. , 'Two genes control aluminum tolerance in maize: Genetic and molecular mapping analyses ' (1999 ) 42 Genome : 475 -482.
Stein, N., Prasad, M., Scholz, U., Thiel, T., Zhang, H.N., Wolf, M., Kota, R., Varshney, R.K., Perovic, D., Grosse, I., Graner, A. 2007. A 1,000-loci transcript map of the barley genome: new anchoring points for integrative grass genomics. Theor. Appl. Genet. 114 :823–839.
Graner A. , 'A 1,000-loci transcript map of the barley genome: new anchoring points for integrative grass genomics ' (2007 ) 114 Theor. Appl. Genet. : 823 -839.
Torii, K.U. 2004. Leucine-rich repeat receptor kinases in plants: Structure, function, and signal transduction pathways. Int. Rev. Cytol. 234 :1–46.
Torii K.U. , 'Leucine-rich repeat receptor kinases in plants: Structure, function, and signal transduction pathways ' (2004 ) 234 Int. Rev. Cytol. : 1 -46.
Von Uexkull, H.R., Mutert, E. 1995. Global extent, development and economic-impact of acid soils. Plant and Soil 171 :1–15.
Mutert E. , 'Global extent, development and economic-impact of acid soils ' (1995 ) 171 Plant and Soil : 1 -15.
Wang, J.P., Raman, H., Read, B., Zhou, M.X., Mendham, N., Venkatanagappa, S. 2006. Validation of an Alt locus for aluminium tolerance scored with eriochrome cyanine R staining method in barley cultivar Honen( Hordeum vulgare L.). Aust. J. Agric. Res. 57 :113–118.
Venkatanagappa S. , 'Validation of an Alt locus for aluminium tolerance scored with eriochrome cyanine R staining method in barley cultivar Honen(Hordeum vulgare L.) ' (2006 ) 57 Aust. J. Agric. Res. : 113 -118.
Wang, J.P., Raman, H., Zhou, M.X., Ryan, P.R., Delhaize, E., Hebb, D.M., Coombes, N., Mendham, N. 2007. High-resolution mapping of the Alp locus and identification of a candidate gene HvMATE controlling aluminium tolerance in barley ( Hordeum vulgare L.). Theor. Appl. Genet. 115 :265–276.
Mendham N. , 'High-resolution mapping of the Alp locus and identification of a candidate gene HvMATE controlling aluminium tolerance in barley (Hordeum vulgare L.) ' (2007 ) 115 Theor. Appl. Genet. : 265 -276.
Wolfe, R.I., Franckowiak, J.D. 1991. Multiple dominant and recessive genetic marker stocks in spring barley. Barley Genet. Newsl. 20 :117–121.
Franckowiak J.D. , 'Multiple dominant and recessive genetic marker stocks in spring barley ' (1991 ) 20 Barley Genet. Newsl. : 117 -121.
Xu, S.L., Rahman, A., Baskin, T.I., Kieber, J.J. 2008. Two leucine-rich repeat receptor kinases mediate signalling linking cell wall biosynthesis and ACC Synthase in Arabidopsis . The Plant Cell 20 :3065–3079.
Kieber J.J. , 'Two leucine-rich repeat receptor kinases mediate signalling linking cell wall biosynthesis and ACC Synthase in Arabidopsis ' (2008 ) 20 The Plant Cell : 3065 -3079.
Zhou, L.L., Bai, G.H., Ma, H.X., Carver, B.F. 2007. Quantitative trait loci for aluminum resistance in wheat. Mol. Breed. 19 :153–161.
Carver B.F. , 'Quantitative trait loci for aluminum resistance in wheat ' (2007 ) 19 Mol. Breed. : 153 -161.