The flavonoid biosynthesis pathway yields a large family of phenolic compounds which are involved in many biological activities including plant defense response to a broad spectrum of abiotic and biotic stress factors. In recent years, a wide range of evidences of relationship between the flavonoid biosynthesis and stress has been accumulated based on genetic, physiological and biochemical studies. In this paper, possible mechanisms of counteraction of flavonoid substances to different stress factors are reviewed, and the evidences for relationship between biosynthesis of flavonoid compounds and response to biotic and abiotic stress are summarized with emphasis on cereals.
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