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  • 1 Charles University in Prague Faculty of Pharmacy in Hradec Kralove Heyrovskeho 1203 500 05 Hradec Kralove Czech Republic
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RPTLC retention characteristics have been examined for two series of potential antituberculotic drugs. Various effects were tested which can be manifested in the values of properties measured — i.e. the effect of the type and proportion of the organic component of the mobile phase, and the effect of the pH of the aqueous component of the mobile phase. Experimentally obtained measures of lipophilicity were correlated with each other and with values calculated by a computational method. In this study some substituents, in particular nitro groups or more complicated substitution of the aromatic ring, negatively affected the correlation of the measured values with those calculated.

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Journal of Planar Chromatography - Modern TLC
Language English
Size A4
Year of
Foundation
1988
Volumes
per Year
1
Issues
per Year
6
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0933-4173 (Print)
ISSN 1789-0993 (Online)

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