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  • 1 Faculty of Sciences Institute of Chemistry Trg Dositja Obradovića 3 21000 Novi Sad Yugoslavia
  • 2 Faculty of Pharmacy Vojvode Stepe 450 P.O. Box 146 Belgrade Yugoslavia
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A rapid and simple method has been developed for chromatographic separation of the pharmacologically active components of some antihypertensive drugs. The active compounds — lisinopril, cilazapril, captopril, quinapril, and ramipril — were successfully separated on aminoplast layers with benzene-cyclohexane-methyl ethyl ketone, 15 + 10 + 15 ( v/v ), as mobile phase. The mechanism of retention and the correlation between lipophilicity and log P were both investigated.

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