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  • 1 Universidad de Buenos Aires Cátedra de Química Medicinal, Facultad de Farmacia y Bioquímica Junín 956 (1113) Ciudad Autónoma de Buenos Aires Argentina
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High-performance thin-layer chromatography has been used to follow the synthesis of some quinoxalinone derivatives by biocatalysis in a one-pot reaction, as an alternative route to the poor Hinsberg reaction. The progress of the one-pot reactions can be followed by HPTLC without previous isolation of the different intermediates arising from them. Biocatalytic synthesis of quinoxalinone derivatives leads to an irreversible reaction which gives a single product of high purity and yields in excess of 90–95%.

  • B.M. Fernández and M.I. Abasolo , J. Planar Chromatogr. 3 (1990) 20–23.

    Abasolo M.I. , '' (1990 ) 3 J. Planar Chromatogr. : 20 -23.

  • H. Hinsberg , Liebigs Ann. Chem. 237 (1887) 368–373.

    Hinsberg H. , '' (1887 ) 237 Liebigs Ann. Chem. : 368 -373.

  • K.M. Varshney , J. Planar Chromatogr. 15 (2002) 46–49.

    Varshney K.M. , '' (2002 ) 15 J. Planar Chromatogr. : 46 -49.

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Journal of Planar Chromatography - Modern TLC
Language English
Size A4
Year of
Foundation
1988
Volumes
per Year
1
Issues
per Year
6
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0933-4173 (Print)
ISSN 1789-0993 (Online)

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