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  • 1 National Institute of Chemistry Hajdrihova 19 1000 Ljubljana Slovenia
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A new on-line TLC-MS interface, with computer-controlled extraction of substances from selected spots on a TLC or HPTLC plate, has been constructed. The controlled collection of the sample and its programmed injection into the mass spectrometer is the advantage of this type of interface. The interface has been tested and validated with a standard solution of caffeine as test substance. The results were compared with those from a previously established and now routinely used off-line TLC-SPE-APCI-MS extraction procedure.

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