JPC - Journal of Planar Chromatography - Modern TLC
Volume/Issue:
Volume 17: Issue 4
Planar chromatography of some 1-arylpiperazines behaving as dopaminergic ligands
Authors:
Jelena Veličković University of Belgrade Faculty of Chemistry P.O. Box 158 11001 Belgrade, Serbia and Montenegro

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Deana Andrić University of Belgrade Faculty of Chemistry P.O. Box 158 11001 Belgrade, Serbia and Montenegro

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Goran Roglić University of Belgrade Faculty of Chemistry P.O. Box 158 11001 Belgrade, Serbia and Montenegro

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Živoslav Tešić University of Belgrade Faculty of Chemistry P.O. Box 158 11001 Belgrade, Serbia and Montenegro

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Dušanka Milojković-Opsenica University of Belgrade Faculty of Chemistry P.O. Box 158 11001 Belgrade, Serbia and Montenegro

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Pages:
255–260
Online Publication Date:
08 Mar 2007
Publication Date:
01 Aug 2004
Article Category:
Research Article
DOI:
https://doi.org/10.1556/jpc.17.2004.4.3
Keywords:
Planar Chromatography; Dopaminergic Ligands; Silica; RP-18 silica
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The chromatographic behavior of fourteen 1-arylpiperazine derivatives has been studied by thin-layer chromatography on both silica gel and RP-18 silica gel. Unmodified silica gel was used as polar stationary phase in combination with monocomponent and binary non-polar mobile phases. Binary mobile phases comprising mixtures of methanol, acetone, or dioxane (as organic modifiers) and water were used with RP-18 silica for studies of the chromatographic behavior of the compounds under reversed-phase conditions. An approximately linear relationship was obtained between RM values and the amount of organic modifier in the mobile phases employed. The effect of mobile phase composition on the retention of the substances is discussed, as is the selectivity of the chromatographic systems used. Separation mechanisms are proposed on the basis of the results obtained.

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Cover JPC - Journal of Planar Chromatography - Modern TLC
JPC - Journal of Planar Chromatography - Modern TLC
Print ISSN:
0933-4173
Online ISSN:
1789-0993

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Manuscript Submission: HERE

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Journal of Planar Chromatography - Modern TLC
Language English
Size A4
Year of
Foundation		 1988
Volumes
per Year		 1
Issues
per Year		 6
Founder Akadémiai Kiadó
Founder's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher		 Chief Executive Officer, Akadémiai Kiadó
ISSN 0933-4173 (Print)
ISSN 1789-0993 (Online)

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