JPC - Journal of Planar Chromatography - Modern TLC
Volume/Issue:
Volume 20: Issue 2
Modeling of thin-layer chromatographic separation of androstane isomers
Authors: Lorentz Jäntschi 1 , Sorin Hodişan 2 , Claudia Cimpoiu 3 , Anamaria Hosu 3 , Eugen Darvasi 3 , and Teodor Hodişan 3
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  • 1 Technical University 15 C. Daicoviciu 400020 Cluj-Napoca Romania
  • 2 University of Oradea Faculty of Sciences 5 Armata Română 410087 Oradea Romania
  • 3 ‘Babeş-Bolyai’ University Faculty of Chemistry and Chemical Engineering 11 Arany Janos 400028 Cluj-Napoca Romania
DOI:
https://doi.org/10.1556/jpc.20.2007.2.4
Page Count:
91–94
Publication Date:
01 Apr 2007
Online Publication Date:
23 Apr 2007
Article Category:
Research Article
Restricted access

Modeling of thin-layer chromatographic separation of androstane isomers to find the optimum mobile phase is described in this paper. The isomers of androstane are present in a variety of samples, so achieving their optimum thin-layer chromatographic separation is very important. A mathematical model was developed and tested. The model takes into account the interaction between solvents and uses a complex function for modeling, so it provides reliable results. The proposed mathematical model gives results similar to those obtained by use of other optimization models, for example the ‘Simplex’ and ‘Prisma’ methods.

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Cover JPC - Journal of Planar Chromatography - Modern TLC
JPC - Journal of Planar Chromatography - Modern TLC
Print ISSN:
0933-4173
Online ISSN:
1789-0993
Keywords:
Androstane isomers; Separation modeling; Thin-layer chromatography; Mobile-phase optimization

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