The BioArena system, which integrates the modern technique and biological results of bioautography with layer liquid chromatography is especially suitable for investigating biochemical interactions. Formaldehyde (HCHO) and its reaction products play a crucial role in the antibiotic activity of
-resveratrol and other molecules — when HCHO-capturing molecules are used in culture media the antimicrobial activity of antibiotic-like compounds decreases substantially. HCHO and hydrogen peroxide are present as normal endogenous compounds in cells, so there is a possibility of interaction in which singlet oxygen (
) and excited HCHO can be formed. The
can oxidize water molecules and so H
can be formed, from which, by disproportion, among other reactions, ozone (O
) also can be formed in the chromatographic spots. Elimination of HCHO and/or O
from the spots results in a decrease in the antiproliferative effect.
, Double Immune Response of Plants to Pathogens and its Biochemical Basis. In:
J.A. Teixeira da Silva
(Ed.) Foliculture, Ornamental and Plant Biotechnology, Advances and Topical Issues, Vol. 3, Global Science Books, London, UK, 2006, pp. 380–388.
Tyihák E., '', in Foliculture, Ornamental and Plant Biotechnology, Advances and Topical Issues, Vol. 3, (2006) -.
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P. Wentworth Jr, A.D. Wentworth, X.Y. Zhu, I.A. Wilson, K.D. Janda, A. Eschenmoser
, Proc. Natl. Acad. Sci. USA