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  • 1 D.G. Ruparel College Department of Chemistry Mahim, Mumbai 400016 India
  • | 2 SVKM’s NMIMS Department of Pharmaceutical Chemistry, School of Pharmacy & Technology Management Vile Parle, Mumbai 400056 India
  • | 3 Guru Nanak Institute of Research and Development Department of Chemistry Matunga, Mumbai 400019 India
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A simple high-performance thin-layer chromatographic (HPTLC) method has been established for simultaneous quantification of penta-O-galloyl-β-d-glucose (PGG), tetra-O-galloyl-β-d-glucose (TGG), chebulinic acid, chebulagic acid, and gallic acid from different samples of Triphala churna: TC1, TC2, TC3, TC4, Hirda, Behda, Amla. The method was validated for precision (expressed as coefficient of variation, CV [%]), accuracy, sensitivity, and selectivity. The accuracy of the method was determined by measurement of the recovery at three different concentrations. Average recovery was 98.46% for PGG, 100.02% for TGG, 100.05% for chebulinic acid, 99.79% for chebulagic acid, and 101.15% for gallic acid from Triphala churna. The proposed HPTLC method was found to be simple, precise, selective, sensitive, and accurate for routine quality control of the different samples of Triphala churna containing hydrolyzable tannins.

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Journal of Planar Chromatography - Modern TLC
Language English
Size A4
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1988
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Springer Nature Switzerland AG
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ISSN 0933-4173 (Print)
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