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  • 1 Maria Curie-Skłodowska University Department of Physical Chemistry, Faculty of Chemistry Maria Curie-Skłodowska Sq. 3 20-031 Lublin Poland
  • | 2 Medical University Department of Organic Chemistry, Faculty of Pharmacy 6 Staszica St. 20-081 Lublin Poland
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Lipophilicities of 21 newly synthesized 1,2,4-triazoles, compounds of potential importance as fungicides, have been determined by micellar and reversed-phase planar chromatography. Different stationary and mobile phases were used in the measurements. Chromatographic lipophilicities (log km and RM0) were correlated with partition coefficients log P (Alog Ps, AClog P, Alog P, Mlog P, KowWin, xlog P2 and xlog P3) calculated from molecular structures. Principal component analysis allowed a more objective comparison of different lipophilicity descriptors determined from various chromatographic systems and calculated theoretically as log P parameters.

  • S. Gocan, G. Cipman, J. Comer, in: E. Grushka, N. Grinberg (eds.), Advances in Chromatography, Vol. 44. Taylor & Francis Group, London, 2005.

    Comer J. , '', in Advances in Chromatography, Vol. 44 , (2005 ) -.

  • R. Kaliszan, Quantitative Structure-Chromatographic Retention Relationships. John Wiley & Sons, New York, 1987.

    Kaliszan R. , '', in Quantitative Structure-Chromatographic Retention Relationships , (1987 ) -.

  • J. Sangster, Octanol-Water Partition Coefficients: Fundamentals and Physical Chemistry. John Wiley & Sons, New York, 1997.

    Sangster J. , '', in Octanol-Water Partition Coefficients: Fundamentals and Physical Chemistry , (1997 ) -.

  • R. Kaliszan, Anal. Chem. 64 (1992) 619A–631A.

    Kaliszan R. , '' (1992 ) 64 Anal. Chem. : 619A -631A.

  • R.J. Krieger, Handbook of Pesticide Toxicology: Principles. Academic Press, San Diego, 2001.

    Krieger R.J. , '', in Handbook of Pesticide Toxicology: Principles , (2001 ) -.

  • C.A. Lipiński, F. Lombardo, B.W. Dominy, P.J. Feeney, Adv. Drug Delivery Rev. 46 (2001) 3–26.

    Feeney P.J. , '' (2001 ) 46 Adv. Drug Delivery Rev. : 3 -26.

  • A. Nasal, D. Siluk, R. Kaliszan, Curr. Med. Chem. 10 (2003) 381–426.

    Kaliszan R. , '' (2003 ) 10 Curr. Med. Chem. : 381 -426.

  • J. Sherma, J. AOAC Int. 86 (2003) 602–611.

    Sherma J. , '' (2003 ) 86 J. AOAC Int. : 602 -611.

  • S.K. Poole, C.F. Poole, J. Chromatogr. B 797 (2003) 3–19.

    Poole C.F. , '' (2003 ) 797 J. Chromatogr. B : 3 -19.

  • K. Valkó, J. Chromatogr. A 1037 (2004) 299–310.

    Valkó K. , '' (2004 ) 1037 J. Chromatogr. A : 299 -310.

  • K. Héberger, J. Chromatogr. A 1158 (2007) 273–305.

    Héberger K. , '' (2007 ) 1158 J. Chromatogr. A : 273 -305.

  • M. Kah, C.D. Brown, Chemosphere 72 (2008) 1401–1408.

    Brown C.D. , '' (2008 ) 72 Chemosphere : 1401 -1408.

  • D. Casoni, A. Kot-Wasik, J. Namieśnik, C. Sârbu, J. Chromatogr. A 1216 (2009) 2456–2465.

    Sârbu C. , '' (2009 ) 1216 J. Chromatogr. A : 2456 -2465.

  • Ł. Komsta, R. Skibiński, A. Berecka, A. Gumieniczek, B. Radkiewicz, M. Radoń, J. Pharm. Biomed. Anal. 53 (2010) 911–918.

    Radoń M. , '' (2010 ) 53 J. Pharm. Biomed. Anal. : 911 -918.

  • Q.S. Wang, L. Zhang, J. Liq. Chromatogr. Relat. Technol. 22 (1999) 1–14.

    Zhang L. , '' (1999 ) 22 J. Liq. Chromatogr. Relat. Technol. : 1 -14.

  • D. Vracas, C. Giaginis, A, Tsantili-Kakoulidou, J. Chromatogr. A 1116 (2006) 158–164.

    Tsantili-Kakoulidou A. , '' (2006 ) 1116 J. Chromatogr. A : 158 -164.

  • J. Yin, H. Liu, C. Pidgeon, Bioorg. Med. Chem. Lett. 8 (1998) 179–182.

    Pidgeon C. , '' (1998 ) 8 Bioorg. Med. Chem. Lett. : 179 -182.

  • M. Turowski, R. Kaliszan, J. Pharm. Biomed. Anal. 15 (1997) 1325–1333.

    Kaliszan R. , '' (1997 ) 15 J. Pharm. Biomed. Anal. : 1325 -1333.

  • M.A. Al-Haj, P. Haber, R. Kaliszan, B. Buszewski, M. Jezierska, Z. Chilmonczyk, J. Pharm. Biomed. Anal. 18 (1998) 721–728.

    Chilmonczyk Z. , '' (1998 ) 18 J. Pharm. Biomed. Anal. : 721 -728.

  • B. Buszewski, M. Jezierska, M. Wełniak, R. Kaliszan, J. Chromatogr. A 845 (1999) 433–445.

    Kaliszan R. , '' (1999 ) 845 J. Chromatogr. A : 433 -445.

  • A. Berthod, S. Carda-Broch, M.C. Garcia-Alvarez-Coque, Anal. Chem. 71 (1999) 879–888.

    Garcia-Alvarez-Coque M.C. , '' (1999 ) 71 Anal. Chem. : 879 -888.

  • S. Carda-Broch, A. Berthod, J. Chromatogr. A 995 (2003) 55–66.

    Berthod A. , '' (2003 ) 995 J. Chromatogr. A : 55 -66.

  • M.J. Medina-Hernández, S. Sagrado, J. Chromatogr. A 718 (1995) 273–282.

    Sagrado S. , '' (1995 ) 718 J. Chromatogr. A : 273 -282.

  • L. Escuder-Gilabert, S. Sagrado, R.M. Villanueva-Camaáns, M.J. Medina-Hernández, Anal. Chem. 70 (1998) 28–34.

    Medina-Hernández M.J. , '' (1998 ) 70 Anal. Chem. : 28 -34.

  • M.G. Khaledi, E.D. Breyer, Anal. Chem. 61 (1989) 1040–1047.

    Breyer E.D. , '' (1989 ) 61 Anal. Chem. : 1040 -1047.

  • H. Nishi, J. Chromatogr. A 780 (1997) 243–264.

    Nishi H. , '' (1997 ) 780 J. Chromatogr. A : 243 -264.

  • L. Escuder-Gilabert, J.J. Martínez-Pla, S. Sagrado, R.M. Villanueva—Camaáns, M.J. Medina-Hernández, J. Chromatogr. B 797 (2003) 21–35.

    Medina-Hernández M.J. , '' (2003 ) 797 J. Chromatogr. B : 21 -35.

  • M.J. Ruiz-Angel, S. Carda-Broch, M.C. García-Alvarez-Coque, A. Berthod, J. Chromatogr. A 1030 (2004) 279–288.

    Berthod A. , '' (2004 ) 1030 J. Chromatogr. A : 279 -288.

  • S.S. Shtykov, E.G. Sumina, N.V. Tyurina, J. Anal. Chem. 57 (2002) 322–325.

    Tyurina N.V. , '' (2002 ) 57 J. Anal. Chem. : 322 -325.

  • M. Janicka, D. Pietras-Ożga, J. Planar Chromatogr. 23 (2010) 396–399.

    Pietras-Ożga D. , '' (2010 ) 23 J. Planar Chromatogr. : 396 -399.

  • P. Kawczak, Y. Vander Heyden, A. Nasal, T. Bączek, A. Drabczyńska, K. Kieć-Kononowicz, R. Kaliszan, J. Sep. Sci. 33 (2010) 1546–1557.

    Kaliszan R. , '' (2010 ) 33 J. Sep. Sci. : 1546 -1557.

  • A. Berthod, C. Garcia-Alvarez-Coque, Micellar Liquid Chromatography, Vol. 83. Marcel Dekker Inc., New York, 2001.

    Garcia-Alvarez-Coque C. , '', in Micellar Liquid Chromatography, Vol. 83 , (2001 ) -.

  • W. Klotz, M.R. Schure, J.P. Foley, J. Chromatogr. A 930 (2001) 145–154.

    Foley J.P. , '' (2001 ) 930 J. Chromatogr. A : 145 -154.

  • W. Klotz, M.R. Schure, J.P. Foley, J. Chromatogr. A 962 (2002) 207–219.

    Foley J.P. , '' (2002 ) 962 J. Chromatogr. A : 207 -219.

  • T. Cserháti, J. Liq. Chromatogr. 16 (1993) 1805–1817.

    Cserháti T. , '' (1993 ) 16 J. Liq. Chromatogr. : 1805 -1817.

  • T. Cserháti, Chromatographia 18 (1984) 18–20.

    Cserháti T. , '' (1984 ) 18 Chromatographia : 18 -20.

  • T. Cserháti, Chromatographia 18 (1984) 318–322.

    Cserháti T. , '' (1984 ) 18 Chromatographia : 318 -322.

  • K. Valkó, J. Liq. Chromatogr. 7 (1984) 1405–1424.

    Valkó K. , '' (1984 ) 7 J. Liq. Chromatogr. : 1405 -1424.

  • C. Sârbu, S. Todor, J. Chromatogr. A 822 (1998) 263–269.

    Todor S. , '' (1998 ) 822 J. Chromatogr. A : 263 -269.

  • T. Djaković-Sekulić, C. Sârbu, N.U. Perišić-Janjić, 18 (2005) 432–436

  • E. Petriková, K. Waisser, J. Planar Chromatogr. 24 (2011) 196–200.

    Waisser K. , '' (2011 ) 24 J. Planar Chromatogr. : 196 -200.

  • R. Skibiński, T. Sławik, M. Kaczkowska, J. Planar Chromatogr. 24 (2011) 348–351.

    Kaczkowska M. , '' (2011 ) 24 J. Planar Chromatogr. : 348 -351.

  • E. Soczewiński, C.A. Wachtmeister, J. Chromatogr. 7 (1962) 311–317.

    Wachtmeister C.A. , '' (1962 ) 7 J. Chromatogr. : 311 -317.

  • E. Soczewiński, J. Chromatogr. A 965(1–2) (1992) 109–116.

    Soczewiński E. , '' (1992 ) 965 J. Chromatogr. A : 109 -116.

  • M.C. Garcia-Alvarez-Coque, J.R. Torres-Lapasió, J.J. Baeza-Baeza, J. Chromatogr. A 780 (1997) 129–148.

    Baeza-Baeza J.J. , '' (1997 ) 780 J. Chromatogr. A : 129 -148.

  • O. Jiménez, M.L. Marina, J. Chromatogr. A 780 (1997) 149–163.

    Marina M.L. , '' (1997 ) 780 J. Chromatogr. A : 149 -163.

  • J.P. Foley, Anal. Chim. Acta. 231 (1990) 237–247.

    Foley J.P. , '' (1990 ) 231 Anal. Chim. Acta. : 237 -247.

  • K. Galewicz-Walesa, A. Pachuta-Stec, Annales UMSC sectio AA LVIII 9 (2003) 118–125.

    Pachuta-Stec A. , '' (2003 ) 9 Annales UMSC sectio AA LVIII : 118 -125.

  • E. Mendyk, A. Drzewiecka, A. Pachuta-Stec, T. Lis, A.E Kozioł, Struct. Chem. 22 (2011) 211–223.

    Kozioł A.E. , '' (2011 ) 22 Struct. Chem. : 211 -223.

  • E. Mincsovics, M. Garami, L. Kecskés, B. Tapa, Z. Végh, Gy. Kátay, E. Tyihák, J. AOAC Int. 82 (1997) 587–598.

    Tyihák E. , '' (1997 ) 82 J. AOAC Int. : 587 -598.

  • E. Tyihák, E. Mincsovics, in: Sz. Nyiredy (ed.) Planar Chromatography. A Retrospective View for the Third Millennium. Springer, Budapest, Hungary, 2000.

    Mincsovics E. , '', in Planar Chromatography. A Retrospective View for the Third Millennium , (2000 ) -.

  • I.V. Tetko, V.Yu. Tanchuk, VCCLAB 2004; http://146.107.217.178

  • I.V. Tetko, J. Gasteiger, R. Todeschini, A. Mauri, D. Livingstone, P. Ertl, V.A. Palyulin, E.V. Radchenko, N.S. Zefirov, A.S. Makarenko, V.Yu. Tanchuk, V.V. Prokopenko, J. Comput. Aid Mol. Des. 19 (2005) 453–463.

    Prokopenko V.V. , '' (2005 ) 19 J. Comput. Aid Mol. Des. : 453 -463.

  • M. Janicka, K. Stępnik, A. Pachuta-Stec, Chromatographia 75 (2012) 449–456.

    Pachuta-Stec A. , '' (2012 ) 75 Chromatographia : 449 -456.

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