Authors:
Dezső Csupor University of Szeged, Eötvös Street 6, H-6720 Szeged, Hungary
University of Szeged, Eötvös Street 6, H-6720 Szeged, Hungary

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Ákos Micsinay University of Szeged, Eötvös Street 6, H-6720 Szeged, Hungary
University of Szeged, Eötvös Street 6, H-6720 Szeged, Hungary

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Imre Máthé University of Szeged, Eötvös Street 6, H-6720 Szeged, Hungary
University of Szeged, Eötvös Street 6, H-6720 Szeged, Hungary

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Klára Horváth-Boros University of Szeged, Eötvös Street 6, H-6720 Szeged, Hungary
University of Szeged, Eötvös Street 6, H-6720 Szeged, Hungary

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Tivadar Kiss University of Szeged, Eötvös Street 6, H-6720 Szeged, Hungary
University of Szeged, Eötvös Street 6, H-6720 Szeged, Hungary

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Judit Hohmann University of Szeged, Eötvös Street 6, H-6720 Szeged, Hungary
University of Szeged, Eötvös Street 6, H-6720 Szeged, Hungary

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Grapefruit (Citrus paradisi) seeds are increasingly applied for medicinal purposes, especially due to their antimicrobial and immunostimulant features, to treat or prevent common cold. However, the scientific background of these uses has not been established. To date, only in vitro studies support the antimicrobial effect of the seeds, and there are no data on the systemic antibiotic or other clinical effects. Moreover, recent data refer to the adulteration of grapefruit seed products with synthetic antiseptics which may be an explanation for the antimicrobial efficacy of some formulations. The aim of our study was to develop a simple thin-layer chromatography- based method for the quality control of grapefruit seed extracts. Besides the analytical procedure, we report a quick and simple method for the isolation of limonoids from grapefruit seeds. Limonoids are characteristic compounds of the seeds; hence, the detection of these marker compounds may be the basis of grapefruit identification. Further, a thin-layer chromatographic screening for synthetic antiseptics (quaternary ammonium salts) is also part of the quality control procedure.

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Journal of Planar Chromatography - Modern TLC
Language English
Size A4
Year of
Foundation
1988
Volumes
per Year
1
Issues
per Year
6
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0933-4173 (Print)
ISSN 1789-0993 (Online)

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