University of Szeged, Eötvös Street 6, H-6720 Szeged, Hungary
Search for other papers by Dezső Csupor in
Current site
Google Scholar
PubMed
University of Szeged, Eötvös Street 6, H-6720 Szeged, Hungary
Search for other papers by Ákos Micsinay in
Current site
Google Scholar
PubMed
University of Szeged, Eötvös Street 6, H-6720 Szeged, Hungary
Search for other papers by Imre Máthé in
Current site
Google Scholar
PubMed
University of Szeged, Eötvös Street 6, H-6720 Szeged, Hungary
Search for other papers by Klára Horváth-Boros in
Current site
Google Scholar
PubMed
University of Szeged, Eötvös Street 6, H-6720 Szeged, Hungary
Search for other papers by Tivadar Kiss in
Current site
Google Scholar
PubMed
University of Szeged, Eötvös Street 6, H-6720 Szeged, Hungary
Search for other papers by Judit Hohmann in
Current site
Google Scholar
PubMed
Grapefruit (Citrus paradisi) seeds are increasingly applied for medicinal purposes, especially due to their antimicrobial and immunostimulant features, to treat or prevent common cold. However, the scientific background of these uses has not been established. To date, only in vitro studies support the antimicrobial effect of the seeds, and there are no data on the systemic antibiotic or other clinical effects. Moreover, recent data refer to the adulteration of grapefruit seed products with synthetic antiseptics which may be an explanation for the antimicrobial efficacy of some formulations. The aim of our study was to develop a simple thin-layer chromatography- based method for the quality control of grapefruit seed extracts. Besides the analytical procedure, we report a quick and simple method for the isolation of limonoids from grapefruit seeds. Limonoids are characteristic compounds of the seeds; hence, the detection of these marker compounds may be the basis of grapefruit identification. Further, a thin-layer chromatographic screening for synthetic antiseptics (quaternary ammonium salts) is also part of the quality control procedure.
-
[1]
S. Carrington , H. Fraser, J. Gilmore, A. Forde, A–Z of Barbados Heritage, Macmillan Caribbean A–Z Series, Macmillan Publishers, Oxford, 2003.
-
[2]
S. Milind , Citrus Fruit Biology, Technology and Evaluation, Academic Press, San Diego, CA, 2008.
-
[3]
F. Anwar , R. Naseer, M.I. Bhanger, S. Ashraf, F.N. Talpur, F.A. Aladedunye, J. Am. Oil Chem. Soc. 85 (2008) 321–330.
-
[4]
K.K. Mandadi , G.K. Jayaprakasha, N.G. Bhat, B.S. Patil, Z. Naturforsch. C 62 (2007) 179–188.
-
[5]
G. Takeoka , L. Dao, R.Y. Wong, R. Lundin, N. Mahoney, J. Agric. Food Chem. 49 (2001) 3316–3320.
-
[6]
K. Fukuda , T. Ohta, Y. Oshima, N. Ohashi, M. Yoshikawa, Y. Yamazoe, Pharmacogenetics 7 (1997) 391–396.
-
[7]
K. He , K.R. Iyer, R.N. Hayes, M.W. Sinz, T.F. Woolf, P.F. Hollenberg, Chem. Res. Toxicol. 11 (1998) 252–259.
-
[8]
H. Wangensteen , E. Molden, H. Christensen, K.E. Malterud, Eur. J. Clin. Pharmacol. 58 (2003) 663–668.
-
[9]
A. Vikram , P.R. Jesudhasan, G.K. Jayaprakasha, B.S. Pillai, B.S. Patil, Int. J. Food Microbiol. 140 (2010) 109–116.
-
[10]
L. Reagor , J. Gusman, L. McCoy, E. Carino, J.P. Heggers, J. Altern. Complement. Med. 8 (2002) 325–332.
-
[11]
T. von Woedtke , B. Schluter, P. Pflegel, U. Lindequist, W.D. Julich, Pharmazie 54 (1999) 452–456.
-
[12]
G. Ionescu , R. Kiehl, F. Wichmann-Kunz, C. Williams, L. Bäuml, S. Levine, J. Orthomol. Med. 5 (1990) 155–157.
-
[13]
O.A. Oyelami , E.A. Agbakwuru, L.A. Adeyemi, G.B. Adedeji, J. Altern. Complement. Med. 11 (2005) 369–371.
-
[14]
S. Pomkeua , Chemical constituents from the rhizomes of curcuma zeoaria (Christm.) rosc. and the stems of citrus medica Linn., Thesis, Prince of Songkla University, Chang Wat Songkhla (Thailand), 2010.
-
[15]
J.H. Lee , B.W. Lee, Y.H. Moon, M.S. Yang, K.C. Jang, K.H. Park, Appl. Biol. Chem. 48 (2005) 93–96.
-
[16]
Opinion of the scientific committee on cosmetic products and non-food products intended for consumers concerning benzethonium chloride (SCCNFP/0539/01), 2002 (online); http://ec.europa.eu/health/ph_risk/committees/sccp/documents/out158_en.pdf. (accessed: July 7, 2017).
-
[17]
H. Brandin , O. Myrberg, T. Rundlof, A.-K. Arvidsson, G. Brenning, Eur. J. Clin. Pharmacol. 63 (2007) 565–570.
To see the editorial board, please visit the website of Springer Nature.
Manuscript Submission: HERE
For subscription options, please visit the website of Springer Nature.
| Journal of Planar Chromatography - Modern TLC | |
|---|---|
| Language | English |
| Size | A4 |
| Year of Foundation |
1988 |
| Volumes per Year |
1 |
| Issues per Year |
6 |
| Founder | Akadémiai Kiadó |
| Founder's Address |
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245. |
| Publisher | Akadémiai Kiadó Springer Nature Switzerland AG |
| Publisher's Address |
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245. CH-6330 Cham, Switzerland Gewerbestrasse 11. |
| Responsible Publisher |
Chief Executive Officer, Akadémiai Kiadó |
| ISSN | 0933-4173 (Print) |
| ISSN | 1789-0993 (Online) |
Monthly Content Usage
| Abstract Views | Full Text Views | PDF Downloads | |
|---|---|---|---|
| Nov 2024 | 73 | 0 | 0 |
| Dec 2024 | 99 | 0 | 0 |
| Jan 2025 | 32 | 1 | 1 |
| Feb 2025 | 64 | 0 | 0 |
| Mar 2025 | 71 | 0 | 0 |
| Apr 2025 | 25 | 1 | 1 |
| May 2025 | 10 | 0 | 0 |
Copyright Akadémiai Kiadó AKJournals is the trademark of Akadémiai Kiadó's journal publishing business branch.