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Absztrakt

A szívelégtelenség magas prevalenciájú, a gyógyszeres terápiában tapasztalható fejlődés ellenére is rossz prognózisú betegség. A reszinkronizációs terápia biventricularis pacemakerrel az intraventricularis vezetési zavarral szövődött súlyos szívelégtelenség számos klinikai tanulmányban bizonyított hatékonyságú kezelési módja. Hagyományosan az indikáció alapja a súlyos szívelégtelenség (NYHA III-IV.) optimális gyógyszeres kezelés mellett, megnyúlt QRS időtartam (≥120 ms), echocardiographiás paraméterek (bal kamrai ejectiós frakció legfeljebb 35%). Új módszerek bevezetése (szöveti doppler echocardiograp-hia, CT, MRI, elektroanatómiai térképezés) segíthetnek a potenciálisan responder betegek kiválasztásában. Non-invazív és invazív módszerek segítségével a kezelés individuális beállítása elvégezhető, a hatékonyság responder betegeknél is fokozható. A reszinkronizáció kiemelkedő hatékonysága miatt az indikációs kör szélesítése is cél. Jelenleg enyhe szívelégtelenségben, illetve keskeny QRS esetén vizsgálják a kezelés hatékonyságát. Számos egyéb kérdésre (transzvénás vagy sebészi implantáció, implantálható de-fibrillator szükségessége) csak a jövőben tervezett vizsgálatok adhatnak választ.

  • 1. K Swedberg J Cleland H Dargie H Drexler F Follath M Komajda L Tavazzi OA Smiseth A Gavazzi A Haverich A Hoes T Jaarsma J Korewicki S Levy C Linde JL Lopez-Sendon MS Nieminen L Pierard WJ Remme 2005 Task Froce for the Diagnosis and Treatment of Chronic Heart Failure of the European Society of Cardiology: Guidelines for the diagnosis and treatment of chronic heart failure: executive summary (update 2005): The Task Force for the Diagnosis and Treatment of Chronic Heart Failure of the European Society of Cardiology. Eur Heart J 26 1115 40.

    • Search Google Scholar
    • Export Citation
  • 2. JN Cohn SO Goldstein BH Greenberg BH Lorell RC Bourge BE Jaski SO Gottlieb F, 3rd McGrew DL DeMets BG White 1998 A dose-dependent increase in mortality with vesnarinone among patients with severe heart failure. Vesnarinone Trial Investigators. N Engl J Med 339 25 1810 6.

    • Search Google Scholar
    • Export Citation
  • 3. JJ Bax T Abraham SS Barold OA Breithardt JW Fung S Garrigue J, 3rd Gorcsan DL Hayes DA Kass J Knuuti C Leclercq C Linde DB Mark MJ Monaghan P Nihoyannopoulos MJ Schalij C Stellbrink CM Yu 2005 Cardiac resynchronization therapy part 1 - Issues before device implantation. J Am Coll Cardiol 46 12 2153 67.

    • Search Google Scholar
    • Export Citation
  • 4. MR Bristow LA Saxon J Boehmer S Krueger DA Kass T De Marco P Carson L DiCarlo D DeMets BG White DW DeVries AM Feldman 2004 Comparison of Medical Therapy, Pacing, and Defibrillation in Heart Failure (COMPANION) Investigators: Cardiac resynchronization therapy with or without an implantable defibril-lator in advanced chronic heart failure. N Engl J Med 350 2140 50.

    • Search Google Scholar
    • Export Citation
  • 5. JG Cleland JC Daubert E Erdmann N Freemantle D Gras L Kappenberger L Tavazzi 2006 Longer-term effects of cardiac resynchronization therapy on mortality in heart failure [the CArdiac Resynchronization-Heart Failure (CARE-HF) trial extension phase]. Eur Heart J 27 16 1928 32.

    • Search Google Scholar
    • Export Citation
  • 6. M Rivero-Ayerza DA Theuns HM Garcia-Garcia E Boersma M Simoons LJ Jordaens 2006 Effects of cardiac resynchronization therapy on overall mortality and mode of death: a meta-analysis of randomized controlled trials. Eur Heart J 27 2682 8.

    • Search Google Scholar
    • Export Citation
  • 7. RN Doshi EG Daoud C Fellows K Turk A Duran MH Hamdan LA Pires 2004 PAVE Study Group: Ablate and pace with cardiac resynchronization therapy for patients with reduced ejection fraction: sub-analysis of PAVE study. Heart Rhythm 1 5 9.

    • Search Google Scholar
    • Export Citation
  • 8. K Zeppenfeld MJ Schalij GB Bleeker ER Holman JJ Bax 2006 Acceleration-dependent left bundle branch block with severe left ventricular dyssynchrony results in acute heart failure: are there more patients who benefit from cardiac resynchronization therapy? J Cardiovasc Electrophysiol 17 1 101 3.

    • Search Google Scholar
    • Export Citation
  • 9. KD Aaronson JS Schwartz TM Chen KL Wong JE Goin DM Mancini 1997 Development and prospective validation of a clinical index to predict survival in ambulatory patients referred for cardiac transplant evaluation. Circulation 17 2660 7.

    • Search Google Scholar
    • Export Citation
  • 10. JG Cleland JC Daubert E Erdmann N Freemantle D Gras L Kappenberger L Tavazzi 2005 Cardiac Resynch-ronization-Heart Failure (CARE-HF) Study Investigators: The effect of cardiac resynchronization on morbidity and mortality in heart failure. N Engl J Med 352 1539 49.

    • Search Google Scholar
    • Export Citation
  • 11. SG Molhoek L van Erven M Bootsma P Steendijk EE Van Der Wall MJ Schalij 2004 QRS duration and shortening to predict clinical response to cardiac resynchronization therapy in patients with end-stage heart failure. Pacing Clin Electrophysiol 27 308 313.

    • Search Google Scholar
    • Export Citation
  • 12. GB Bleeker MJ Schalij SG Molhoek HF Verwey ER Holman E Boersma P Steendijk EE Van Der Wall JJ Bax 2004 Relationship between QRS duration and left ventricular dyssynchrony in patients with end-stage heart failure. J Cardiovasc Electrophysiol 15 5 544 9.

    • Search Google Scholar
    • Export Citation
  • 13. JJ Bax GB Bleeker TH Marwick SG Molhoek E Boersma P Steendijk EE van der Wall MJ Schalij 2004 Left ventricular dysszinchrony predicts response and prognosis after cardiac resynchronization therapy. J Am Coll Cardiol 44 1834 40.

    • Search Google Scholar
    • Export Citation
  • 14. BJ Krenning T Szili-Torok MM Voormolen DA Theuns LJ Jordaens CT Lancee N De Jong AF Van Der Steen FJ Ten Cate JR Roelandt 2004 Guiding and optimization of resynchronization therapy with dynamic three-dimensional echocardiography and segmental volume–time curves: a feasibility study. Eur J Heart Fail 6 5 619 25.

    • Search Google Scholar
    • Export Citation
  • 15. CM Yu WT Abraham J Bax E Chung M Fedewa S Ghio C Leclercq AR Leon J Merlino P Nihoyannopoulos D Notabartolo JP Sun L Tavazzi 2005 PROSPECT Investigators: Predictors of response to cardiac resynchronization therapy (PROSPECT)-study design. Am Heart J 149 600 5.

    • Search Google Scholar
    • Export Citation
  • 16. JJ Westenberg HJ Lamb RJ van der Geest GB Bleeker ER Holman MJ Schalij A de Roos EE van der Wall JH Reiber JJ Bax 2006 Assessment of left ventricular dyssynchrony in patients with conduction delay and idiopathic dilated cardiomyopathy: head-to-head comparison between tissue doppler imaging and velocity-encoded magnetic resonance imaging. J Am Coll Cardiol 47 10 2042 8.

    • Search Google Scholar
    • Export Citation
  • 17. JJ Bax T Abraham SS Barold OA Breithardt JW Fung S Garrigue J Gorcsan 3rd DL Hayes DA Kass J Knuuti C Leclercq C Linde DB Mark MJ Monaghan P Nihoyannopoulos MJ Schalij C Stellbrink CM Yu 2006 Cardiac Resynchronization Therapy Part 2 - Issues during and after device implantation and unresolved questions. J Am Coll Cardiol 46 12 2168 82.

    • Search Google Scholar
    • Export Citation
  • 18. A Roka T Simor H Vago C Minorics G Acsady B Merkely 2004 Magnetic resonance imaging-based biventricular pacemaker upgrade. Pacing Clin Electrophysiol 27 1011 13.

    • Search Google Scholar
    • Export Citation
  • 19. SG Molhoek JJ Bax GB Bleeker E Boersma L van Erven P Steendijk EE van der Wall MJ Schalij 2004 Comparison of response to cardiac resynchronization therapy in patients with sinus rhythm versus chronic atrial fibrillation. Am J Cardiol 94 1506 9.

    • Search Google Scholar
    • Export Citation
  • 20. A Auricchio C Fantoni F Regoli C Carbucicchio A Goette C Geller M Kloss H Klein 2004 Characterization of left ventricular activation in patients with heart failure and left bundle branch block. Circulation 109 1133 1139.

    • Search Google Scholar
    • Export Citation
  • 21. JB Young WT Abraham AL Smith AR Leon R Lieberman B Wilkoff RC Canby JS Schroeder LB Liem S Hall K Wheelan 2004 Multicenter InSync ICD Randomized Clinical Evaluation (MIRACLE ICD) Trial Investigators: Combined cardiac resynchronization and implantable cardioversion defibrillation in advanced chronic heart failure: the MIRACLE-ICD trial. Circulation 110 2864 8.

    • Search Google Scholar
    • Export Citation
  • 22. C Linde M Gold WT Abraham JC Daubert 2006 REVERSE Study Group: Rationale and design of a randomized controlled trial to assess the safety and efficacy of cardiac resynchronization therapy in patients with asymptomatic left ventricular dysfunction with previous symptoms or mild heart failure - the Resynchronization reVErses Remodeling in Systolic left vEntricular dysfunction (REVERSE) study. Am Heart J 151 2 288 94.

    • Search Google Scholar
    • Export Citation
  • 23. A Achilli M Sassara S Ficili D Pontillo P Achilli C Alessi S De Spirito R Guerra N Patruno F Serra 2003 Long-term effectiveness of cardiac resynchronization therapy in patients with refractory heart failure and “narrow” QRS. J Am Coll Cardiol 42 2117 24.

    • Search Google Scholar
    • Export Citation
  • 24. SL Higgins P Yong D Sheck M McDaniel F Bollinger M Vadecha S Desai DB Meyer 2000 Ventak CHF Investigators: Biventricular pacing diminishes the need for implantable cardioverter defibrillator therapy. J Am Coll Cardiol 36 3 824 7.

    • Search Google Scholar
    • Export Citation
  • 25. DJ Bradley EA Bradley KL Baughman RD Berger H Calkins SN Goodman DA Kass NR Powe 2003 Cardiac resynchronization and death from progressive heart failure: a meta-analysis of randomized controlled trials. J Am Med Assoc 289 730 40.

    • Search Google Scholar
    • Export Citation
  • 26. R Koos AM Sinha K Markus OA Breithardt K Mischke M Zarse M Schmid R Autschbach P Hanrath C Stellbrink 2004 Comparison of left ventricular lead placement via the coronary venous approach versus lateral thoracotomy in patients receiving cardiac resynchronization therapy. Am J Cardiol 94 59 63.

    • Search Google Scholar
    • Export Citation
  • 27. WT Abraham CW Yancy 2006 Cardiac Resynchronization Therapy: A Practical Guide for Device Optimization, Part I. Congest Heart Fail 12 169 73.

    • Search Google Scholar
    • Export Citation
  • 28. M Vanderheyden T De Backer M Rivero-Ayerza P Geelen J Bartunek S Verstreken M De Zutter M Goethals 2005 Tailored echocardiographic interventricular delay programming further optimizes left ventricular performance after cardiac resynchronization therapy. Heart Rhythm 2 10 1066 72.

    • Search Google Scholar
    • Export Citation
  • 29. G Boriani CP Muller KH Seidl R Grove J Vogt W Danschel A Schuchert P Djiane M Biffi T Becker C Bailleul HJ Trappe 2005 Resynchronization for the HemodYnamic Treatment for Heart Failure Management II Investigators: Randomized comparison of simultaneous biventricular stimulation versus optimized interventri-cular delay in cardiac resynchronization therapy. The Resynchronization for the HemodYnamic Treatment for Heart Failure Management II implantable cardioverter defibrillator (RHYTHM II ICD) study. Am Heart J 151 5 1050 8.

    • Search Google Scholar
    • Export Citation
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Magyar Sebészet
Language Hungarian
Size B5
Year of
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1947
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2021 Volume 74
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1
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4
Founder Magyar Sebész Társaság -- Hungarian Surgical Society
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ISSN 0025-0295 (Print)
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