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  • 1 II. sz. Sebészeti Klinika, Semmelweis Egyetem, Általános Orvostudományi Kar, 1125, Budapest, Kútvölgyi út 4.
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Absztrakt

A pancreascarcinoma praecursorainak tartott intraepithelialis neoplasia (PanIN1–3) és az intraductalis papillaris mucinosus neoplasia (IPMN) hisztopatológiailag és morfológiailag igen heterogén entitás, konzekvens osztályozásuk a közelmútban valósult meg. Áttekintjük a praecancerosisok klinikopatológiai és molekuláris genetikai jellemzőit, melyek az irodalmi adatok szerint egybevágnak az intraepithelialis és intraductalis neoplasiák noninvazív, noninfiltratív viselkedésével, és részben magyarázhatják a pancreas carcinomákétól eltérő, kitűnő prognózisukat.

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