Authors:
György LázárSzegedi Tudományegyetem, Általános Orvostudományi Kar, 6725 Szeged, Semmelweis út 8.

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Attila BursicsFővárosi Önkormányzat Uzsoki Utcai Kórház, Budapest

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Zoltán FarsangÁllami Egészségügyi Központ, Budapest

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László HarsányiSemmelweis Egyetem, Budapest

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Csaba KósaDebreceni Egyetem, Debrecen

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Róbert MarázBács-Kiskun Megyei Önkormányzat Kórháza, Kecskemét

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Zoltán MátraiOrszágos Onkológiai Intézet, Budapest

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Attila PasztSzegedi Tudományegyetem, Általános Orvostudományi Kar, 6725 Szeged, Semmelweis út 8.

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Gábor PavlovicsPécsi Tudományegyetem, Pécs

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Róbert TamásÁllami Egészségügyi Központ, Budapest

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Absztrakt

Az emlőrák sebészi terápiáját napjainkban és a jövőben is az egyre precízebb diagnosztikus módszerek és az egyre hatásosabb onkológiai kezelési eljárások határozzák meg. Az emlőmegtartás és az onkoplasztikai elvek alkalmazása egyre szélesebb körű; az axilla sebészi kezelésében az őrszemnyirokcsomó-biopszia az elsődleges, az axillaris blokkdissectio (ABD) indikációja tovább szűkült, és a sugárkezelés bizonyos esetekben az ABD alternatívája lett. Közleményünkben a III. Emlőrák-konszenzuskonferencia tartalmára épülve, a legfrissebb nemzetközi tanulmányok és szakértői javaslatokat figyelembe véve foglaljuk össze az emlőrák sebészi kezelésével kapcsolatos ajánlásainkat.

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    Flanagan MR, Rendi MH, Calhoun KE, Anderson BO, Javid SH: Pleomorphic lobular carcinoma in situ: Radiologic-pathologic features and clinical management. Ann Surg Oncol 2015; 22: 4263–9

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    Giuliano AE, Hunt KK, Ballman KV, Beitsch PD, Whitworth PW, Blumencranz PW, Leitch AM, Saha S, McCall LM, Morrow M:: Axillary dissection vs no axillary dissection in women with invasive breast cancer and sentinel node metastasis. JAMA 2011; 305: 569–75

  • 25

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  • 26

    Galimberti V, Cole BF, Zurrida S, Viale G, Luini A, Veronesi P, Baratella P, Chifu C, Sargenti M, Intra M, Gentilini O, Mastropasqua MG, Mazzarol G, Massarut S, Garbay JR, Zgajnar J, Galatius H, Recalcati A, Littlejohn D, Bamert M, Colleoni M, Price KN, Regan MM, Goldhirsch A, Coates AS, Gelber RD, Veronesi U; International Breast Cancer Study Group Trial 23-01 investigators: Axillary dissection versus no axillary dissection in patients with sentinel-node micrometastases (IBCSG 23-01): A phase 3 randomised controlled trial. Lancet Oncol 2013; 14: 297–305

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    Sávolt A, Polgár Cs, Musonda P, Mátrai Z, Rényi-Vámos F, Tóth L, Kásler M, Péley G: Does the result of completion axillary lymph node dissection influence the recommendation for adjuvant treatment in sentinel lymph node-positive patients? Clin Breast Cancer 2013; 13: 364-70

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    He PS, Li F, Li GH, Guo C, Chen TJ: The combination of blue dye and radioisotope versus radioisotope alone during sentinel lymph node biopsy for breast cancer: a systematic review. BMC Cancer 2016; 16: 107

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    Maráz R, Boross G, Pap-Szekeres J, Rajtár M, Ambrózay E, Cserni G: Internal mammary sentinel node biopsy in breast cancer. Is it indicated? Pathol Oncol Res 2014; 20: 169–77

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    Sabel MS: The need for axillary lymph node dissection in T1/Tbreast cancer surgery–counterpoint. Cancer Res. 2013; 73: 7156-60

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    Van Uden DJ, van Laarhoven HW, Westenberg AH, de Wilt JH, Blanken-Peeters CF: Inflammatory breast cancer: an overview. Crit Rev Oncol Hematol 2015; 93: 116–26

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    Guidroz JA, Scott-Conner CE, Weigel RJ: Management of pregnant women with breast cancer. J Surg Oncol 2011; 103: 337–40

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    Mátrai Z, Bánhidy F, Téglás M, Kovács E, Sávolt A, Udvarhelyi N, Bartal A, Kásler M: Sentinel lymph node biopsy in pregnancy-associated breast cancer. Orv Hetil 2013; 154: 1991–7

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    Lee HB, Han W: Unique features of young age breast cancer and its management. J Breast Cancer 2014; 17: 301–7

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    Guth U, Myrick ME, Viehl CT, Weber WP, Lardi AM, Schmid SM: Increasing rates of contralateral prophylactic mastectomy – a trend made in USA? Eur J Surg Oncol 2012; 38: 296–301

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    Yao K, Winchester DJ, Czechura T, Huo D: Contralateral prophylactic mastectomy and survival: report from the National Cancer Data Base, 1998–2002. Breast Cancer Res Treat 2013; 142: 465–76

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    Hwang ES, Lichtensztajn DY, Gomez SL, Fowble B, Clarke CA: Survival after lumpectomy and mastectomy for early stage invasive breast cancer: the effect of age and hormone receptor status. Cancer 2013; 119: 1402–11

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