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  • 1 Szent Pantaleon Kórház – Rendelőintézet Dunaújváros, 2400 Dunaújváros, Korányi Sándor u. 4–6.
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  • 3 Szent Pantaleon Kórház – Rendelőintézet Dunaújváros, Dunaújváros
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Esetismertetés: A szerzők egy 78 éves hölgybeteg esetét mutatják be, aki tizenévesként részesült gyógyszeres kezelésben pulmonális tbc miatt, majd a 2015-ben IBD kezelése céljából indított biológiai terápia kapcsán nemcsak légzőszervi tünetei lángoltak fel kb. 60 év tünetmentességet követően, hanem akut has klinikai képe is kialakult. Sürgős műtétre vittük a beteget, ahol vékonybél perforatio miatt segmentresectio történt, a szövettani vizsgálat enterális tbc-t igazolt. A posztoperatív szakban indított gátlószeres kezelés hatására a beteg tünet- és panaszmentessé vált. Megbeszélés: A tuberculosis egy életet veszélyeztető megbetegedés, amely lényegében bármely szervet érintheti. Ezen cikkünkkel szeretnénk felhívni a figyelmet biológiai terápiák, ill. a különböző immunmoduláns kezelések potenciálisan fatális mellékhatásaira és a társszakmák közötti hatékony együttműködés fontosságára.

  • 1

    Holloway KL, Henneberg RJ, de Barros Lopes M, Henneberg M. Evolution of human tuberculosis: A systematic review and meta-analysis of paleopathological evidence. Homo. 2011 Dec; 62(6): 402–458.

  • 2

    Comas I, Coscolla M, Luo T, Borrell S, Holt KE, Kato‑ Maeda M, Parkhill J, Malla B, Berg S, Thwaites G, et al. Out-of-Africa migration and Neolithic coexpansion of Mycobacterium tuberculosis with modern humans. Nat Genet. 2013 Oct; 45(10): 1176–1182.

  • 3

    Escalante P. In the clinic. Tuberculosis. Ann Intern Med. 2009 Jun 2; 150(11): ITC61-614; quiz ITV616.

  • 4

    Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJ. Global and regional burden of disease and risk factors, 2001: Systematic analysis of population health data. Lancet 2006 May 27; 367(9524): 1747–1757.

  • 5

    Miller TL, McNabb SJ, Hilsenrath P, Pasipanodya J, Weis SE. Personal and societal health quality lost to tuberculosis. PLoSOne. 2009; 4(4): e5080.

  • 6

    Chee CBE, Reves R, Zhang Y, Belknap R. Latent tuberculosis infection: Opportunities and challenges. Respirology 2018 Jun 14. . [Epub ahead of print]

    • Crossref
    • Export Citation
  • 7

    WHO Global Tuberculosis Report 2017. (http://www.who.int/tb/publications/global_report/en/)

  • 8

    Centers for Disease Control and Prevention – Tuberculosis Data and Statistics (https://www.cdc.gov/tb/statistics/default.htm)

  • 9

    Wang H, Dwyer-Lindgren L, Lofgren KT, Rajaratnam JK, Marcus JR, Levin-Rector A, Levitz CE, Lopez AD, Murray CJ. Age-specific and sex-specific mortality in 187 countries, 1970–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012 Dec 15; 380 (9859): 2071–2094.

  • 10

    Korányi Bulletin 2018. (http://www.koranyi.hu/tartalom/bulletin/Evkonyv2018.pdf)

  • 11

    Barry CE 3rd, Boshoff HI, Dartois V, Dick T, Ehrt S, Flynn J, Schnappinger D, Wilkinson RJ, Young D. The spectrum of latent tuberculosis: rethinking the biology and intervention strategies. Nat Rev Microbiol. 2009 Dec; 7(12): 845–855.

  • 12

    Zhang Y, Yew WW, Barer MR. Targeting persisters for tuberculosis control. Antimicrob Agents Chemother. 2012 May; 56(5): 2223–2230.

  • 13

    Zhang Y. Persistent and dormant tubercle bacilli and latent tuberculosis. Front Biosci. 2004 May 1; 9: 1136–1156.

  • 14

    Lobue P, Menzies D. Treatment of latent tuberculosis infection: An update. Respirology 2010 May; 15(4): 603–622.

  • 15

    Wang KY, Lin YS, Sy CL, Huang WC, Chen LW. Hyperbaric oxygen therapy increases the risk of tuberculosis disease. Int J Tuberc Lung Dis. 2018 Jun 1; 22(6): 637–640.

  • 16

    Lin PL, Plessner HL, Voitenok NN, Flynn JL. Tumor necrosis factor and tuberculosis. J Investig Dermatol Symp Proc. 2007 May; 12(1): 22–25.

  • 17

    Keane J, Gershon S, Wise RP, et al. Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent. N Engl J Med. 2001; 345: 1098–1104.

  • 18

    Nunez Martinez O, Ripoll Noiseux C, Carneros Martin JA, Gonzalez Lara V, Gregorio Maranon HG. Reactivation tuberculosis in a patient with anti-TNF-alpha treatment. Am J Gastroenterol. 2001; 96: 1665–1666.

  • 19

    Solovic I, Sester M, Gomez-Reino JJ, et al. The risk of tuberculosis related to tumour necrosis factor antagonist therapies: a TBNET consensus statement. Eur Respir J. 2010 Nov; 36(5): 1185–1206.

  • 20

    Stallmach A, Hagel S, Bruns T. Adverse effects of biologics used for treating IBD. Best Pract Res Clin Gastroenterol. 2010 Apr; 24(2): 167–182.

  • 21

    Lalvani A, Millington KA. Screening for tuberculosis infection prior to initiation of anti-TNF therapy. Autoimmun Rev. 2008; 8(2): 147–152.

  • 22

    Dave M, Purohit T, Razonable R, Loftus EV Jr. Opportunistic infections due to inflammatory bowel disease therapy. Inflamm Bowel Dis. 2014 Jan; 20(1): 196–212.

  • 23

    Cohn HM, Dave M, Loftus EV Jr. Understanding the cautions and contraindications of immunomodulator and biologic therapies for use in inflammatory bowel disease. Inflamm Bowel Dis. 2017 Aug; 23(8): 1301–1315.

  • 24

    Berry MP, Graham CM, McNab FW, Xu Z, Bloch SA, Oni T, Wilkinson KA, Banchereau R, Skinner J, Wilkinson RJ, et al. An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis. Nature 2010 Aug 19; 466(7309): 973–977.

  • 25

    Sweeney TE, Braviak L, Tato CM, Khatri P. Genome-wide expression for diagnosis of pulmonary tuberculosis: a multicohort analysis. Lancet Respir Med. 2016 Mar; 4(3): 213–224.

  • 26

    Lu C, Wu J, Wang H, Wang S, Diao N, Wang F, Gao Y, Chen J, Shao L, Weng X, et al. Novel biomarkers distinguishing active tuberculosis from latent infection identified by gene expression profile of peripheral blood mononuclear cells. PLoSOne. 2011; 6(8): e24290.

  • 27

    Verhagen LM, Zomer A, Maes M, Villalba JA, Del Nogal B, Eleveld M, van Hijum SA, de Waard JH, Hermans PW. A predictive signature gene set for discriminating active from latent tuberculosis in Warao Amerindian children. BMC Genomics 2013 Feb 1; 14: 74.

  • 28

    Pan L, Wei N, Jia H, Gao M, Chen X, Wei R, Sun Q, Gu S, Du B, Xing A, et al. Genome-wide transcriptional profiling identifies potential signatures in discriminating active tuberculosis from latent infection. Oncotarget 2017 Dec 4; 8(68): 112907–112916.

  • 29

    Sharma MP, Bhatia V. Abdominal tuberculosis. Indian J Med Res. 2004 Oct; 120(4): 305–315.

  • 30

    Uma Debi, Vasudevan Ravisankar, Kaushal Kishor Prasad, Saroj Kant Sinha, Arun Kumar Sharma. Abdominal tuberculosis of the gastrointestinal tract: Revisited. World J Gastroenterol. 2014 Oct 28; 20(40): 14831–14840.

  • 31

    Ara C, Sogutlu G, Yildiz R, Kocak O, Isik B, Yilmaz S, Kirimlioglu V. Spontaneous small bowel perforations due to intestinal tuberculosis should not be repaired by simple closure. J Gastrointest Surg. 2005 Apr; 9(4): 514–517.

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Language: Papers in Hungarian with abstracts in English

Founded in 1947
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  • Dr. Acsády, György
  • Dr. Bálint, András
  • Dr. Bátorfi, József
  • Dr. Boros, Mihály
  • Dr. Bursics, Attila
  • Dr. Damjanich, László
  • Dr. Gál, István
  • Dr. Gulyás, Gusztáv
  • Dr. Harsányi, László
  • Dr. Horváth, Örs Péter
  • Dr. István, Gábor
  • Dr. Jakab, Ferenc
  • Dr. Kecskés, László
  • Dr. Kupcsulik, Péter
  • Dr. Lázár, György
  • Dr. Lestár, Béla
  • Dr. Metzger, Péter
  • Dr. Molnár, F. Tamás
  • Dr. Nagy, Attila
  • Dr. Oláh, Tibor
  • Dr. Ondrejka, Pál
  • Dr. Romics, László, Jr.
  • Dr. Verebély, Tibor
  • Dr. Vereczkei, András

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