Authors:
P. Collecchi Istituto Nazionale per la Ricerca sul Cancro Laboratorio di Farmacologia Tossicologica Viale Benedetto XV 10-16132 Genova (Italy)

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M. Esposito Istituto Nazionale per la Ricerca sul Cancro Laboratorio di Farmacologia Tossicologica Viale Benedetto XV 10-16132 Genova (Italy)

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S. Meloni Università di Pavia Dipartimento di Chimica Generale Viale Taramelli 12-27100 Pavia (Italy)

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M. Oddone Università di Pavia Dipartimento di Chimica Generale Viale Taramelli 12-27100 Pavia (Italy)

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Abstract  

In recent years much attention has been paid to the presence and role played by trace metals in human tissues and body fluids. Rare-earth element ions are known to have high affinity for calcium binding sites and to antagonize calcium-mediate biological response. The present paper describes an investigation on rare-earth elements abundance in tissue and endogenous plasma of apparently healthy subjects and patients affected by epicondylitis, at the elbow or by laryngeal carcinoma. Some rare-earth elements, namely La, Ce, Nd, Eu, Gd, Yb and Lu were determined by radiochemical neutron activation analysis. Results are presented and discussed as far as precision, accuracy and sensitivity are concerned. The obtained data indicate that rare-earth elements levels in plasma and tissues are significantly affected by the occurence of pathological conditions.

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Journal of Radionalytical and Nuclear Chemistry
Language English
Size A4
Year of
Foundation
1968
Volumes
per Year
1
Issues
per Year
12
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-5731 (Print)
ISSN 1588-2780 (Online)