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  • 1 Hammersmith Hospital MRC Cyclotron Unit Ducane Road W12 OHS London (England)
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An accurate knowledge of the ratio Ca/P in bone biopsies is very useful in the diagnosis of osteoporosis. Similarly, measurements on muscle biopsies are important in understanding the disturbance of intracellular fluid and electrolyte (Na, Cl, K and P) balance in patients with metabolic myopathies (muscle diseases) and acid-base disturbances including renal failure. The ratio Ca/P in normal subjects was found to be 2.30. Similarly, the ratio K/P was found to be very nearly constant in normal subjects.