Multi-element analysis of biological material by RNAA using HPLC with on-line yield determination

J. Woittiez; S. Subramanian; K. Volkers; J. De Goeij

doi:10.1007/bf02040872

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Journal of Radioanalytical and Nuclear Chemistry

Volume/Issue:: Volume 168: Issue 1

Multi-element analysis of biological material by RNAA using HPLC with on-line yield determination

Authors:

J. Woittiez

J. Woittiez Delft University of Technology Interfaculty Reactor Institute Mekelweg 15 2629 JB Delft The Netherlands

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S. Subramanian

S. Subramanian Delft University of Technology Interfaculty Reactor Institute Mekelweg 15 2629 JB Delft The Netherlands

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K. Volkers

K. Volkers Delft University of Technology Interfaculty Reactor Institute Mekelweg 15 2629 JB Delft The Netherlands

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, and

J. De Goeij

J. De Goeij Delft University of Technology Interfaculty Reactor Institute Mekelweg 15 2629 JB Delft The Netherlands

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Pages:: 5–14

Online Publication Date:: 13 Aug 2005

Publication Date:: 01 Feb 1993

Article Category:: Research Article

DOI:: https://doi.org/10.1007/bf02040872

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Abstract

The idea to use high performance liquid chromatography with continuous UV detection for multi-element radiochemical separation and simultaneous multi-element on-line yield determination is introduced. The validity of the concept was evaluated by demonstrating the constancy of the ratio of the signals for a main isotope (⁶⁰Co) and a carrier (⁵⁹Co) as a function of the elemental mass processed in the separation. The suitability of the method for practical purposes is demonstrated by its application to the RNAA determination of cobalt in biological materials. It is concluded that the method, although not yet completely developed, bears the potential of improving both accuracy and precision of multi-element RNAA.

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Journal of Radioanalytical and Nuclear Chemistry

Print ISSN:: 0236-5731

Online ISSN:: 1588-2780

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Journal of Radionalytical and Nuclear Chemistry
Language	English
Size	A4
Year of Foundation	1968
Volumes per Year	1
Issues per Year	12
Founder	Akadémiai Kiadó
Founder's Address	H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher	Akadémiai Kiadó Springer Nature Switzerland AG
Publisher's Address	H-1117 Budapest, Hungary 1516 Budapest, PO Box 245. CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible Publisher	Chief Executive Officer, Akadémiai Kiadó
ISSN	0236-5731 (Print)
ISSN	1588-2780 (Online)