Technetium-99m generators based on neutron irradiated 12-molybdocerate as column matrix

M. El-Absy; I. El-Naggar; A. Audah

doi:10.1007/bf02038002

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Journal of Radioanalytical and Nuclear Chemistry

Volume/Issue:: Volume 183: Issue 2

Technetium-99m generators based on neutron irradiated 12-molybdocerate as column matrix

Authors:

M. El-Absy

M. El-Absy Atomic Energy Establishment Radioisotope Production Department P.O. Code 13759 Cairo (Egypt.)

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I. El-Naggar

I. El-Naggar Atomic Energy Establishment Nuclear Chemistry Department P.O. Code 13759 Cairo (Egypt.)

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A. Audah

A. Audah Atomic Energy Establishment Radioisotope Production Department P.O. Code 13759 Cairo (Egypt.)

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Pages:: 339–350

Online Publication Date:: 14 Aug 2005

Publication Date:: 17 Sep 1994

Article Category:: Research Article

DOI:: https://doi.org/10.1007/bf02038002

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Abstract

Neutron irradiated 12-molybdocerate(IV) is evaluated as a column matrix for use in preparation of small chromatographic column type^99mTc generators. Greater than 87% of the generated^99mTc activity is immediately and reproducibly eluted with passing 10 cm³ of saline or chromated saline solutions through 3.0 g of molybdocerate column bed at flow rates of about 1.0 cm³/min. The elution performance of^99mTc does not drastically change with increasing the drying temperature and/or the particles sixe of the column matrix in the range investigated. Saline eluent containing 5·10^–5M CrO ₄^2– increases the radiochemical purity of the eluate to >98% TcO ₄^– . Radionuclidic and chemical purities of the eluates satisfy the specifications for use in nuclear medicine.

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Journal of Radioanalytical and Nuclear Chemistry

Print ISSN:: 0236-5731

Online ISSN:: 1588-2780

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Journal of Radionalytical and Nuclear Chemistry
Language	English
Size	A4
Year of Foundation	1968
Volumes per Year	1
Issues per Year	12
Founder	Akadémiai Kiadó
Founder's Address	H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher	Akadémiai Kiadó Springer Nature Switzerland AG
Publisher's Address	H-1117 Budapest, Hungary 1516 Budapest, PO Box 245. CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible Publisher	Chief Executive Officer, Akadémiai Kiadó
ISSN	0236-5731 (Print)
ISSN	1588-2780 (Online)