Journal of Radioanalytical and Nuclear Chemistry
Volume/Issue:
Volume 188: Issue 6
An improved procedure for the synthesis of 2-methoxyisobutylisonitrile: An efficient complexing agent for99mTc
Authors:
G. Ferro-Flores Instituto Nacional de Investigaciones Nucleares Department of Radioactive Materials Sierra Mojada 447 Lomas de Barrilaco C.P. 11010 México D.F. México

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L. Ramirez-Garcia Universidad Autonoma del Estado de Morelos Anexo de la Facultad de Ciencias Químicas e Ingeniería Cuernavaca Moralos México

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J. Lezama Instituto Nacional de Investigaciones Nucleares Department of Radioactive Materials Sierra Mojada 447 Lomas de Barrilaco C.P. 11010 México D.F. México

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P. Garcia-Garcia Universidad Autonoma del Estado de Morelos Anexo de la Facultad de Ciencias Químicas e Ingeniería Cuernavaca Moralos México

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J. Tendilla Instituto Nacional de Investigaciones Nucleares Department of Radioactive Materials Sierra Mojada 447 Lomas de Barrilaco C.P. 11010 México D.F. México

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Pages:
409–415
Online Publication Date:
20 Sep 2005
Publication Date:
17 Dec 1994
Article Category:
Research Article
DOI:
https://doi.org/10.1007/bf02164734
Restricted access

Abstract  

99mTc hexakis (2-methoxyisobutylisonitrile) is a cationic complex useful as a myocardial perfusion agent. The synthesis of 2-methoxyisobutylisonitrile (MIBI) by a modified and improved procedure in a two-step process with an overall yield of 53% is described. The preparation of its copper and technetium-99m complexes is also presented.

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Cover Journal of Radioanalytical and Nuclear Chemistry
Journal of Radioanalytical and Nuclear Chemistry
Print ISSN:
0236-5731
Online ISSN:
1588-2780

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Journal of Radionalytical and Nuclear Chemistry
Language English
Size A4
Year of
Foundation		 1968
Volumes
per Year		 1
Issues
per Year		 12
Founder Akadémiai Kiadó
Founder's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher		 Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-5731 (Print)
ISSN 1588-2780 (Online)

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