Radiochemical purity of99mTc radiopharmaceuticals

J. Vučina; D. Vuga; N. Vukićević-Nikolić

doi:10.1007/bf02162476

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Journal of Radioanalytical and Nuclear Chemistry

Volume/Issue:: Volume 199: Issue 2

Radiochemical purity of^99mTc radiopharmaceuticals

Authors:

J. Vučina

J. Vučina Institute of Nuclear Sciences “Vinča” Laboratory for Radioisotopes P.O. Box 522 11001 Belgrade Yugoslavia

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D. Vuga

D. Vuga Institute of Nuclear Sciences “Vinča” Laboratory for Radioisotopes P.O. Box 522 11001 Belgrade Yugoslavia

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, and

N. Vukićević-Nikolić

N. Vukićević-Nikolić Institute of Nuclear Sciences “Vinča” Laboratory for Radioisotopes P.O. Box 522 11001 Belgrade Yugoslavia

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Pages:: 135–142

Online Publication Date:: 27 Sep 2005

Publication Date:: 17 Jan 1995

Article Category:: Research Article

DOI:: https://doi.org/10.1007/bf02162476

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Abstract

Some factors which could adversely affect the integrity of eight routine^99mTc radiopharmaceuticals have been investigated. The radiochemical purity of the preparations was determined both under standard (reconstitution according to the manufacturer's instructions) and under experimental conditions (higher contents of longlived⁹⁹Tc and copper). The influence of radiolytically produced hydrogen peroxide as well as the effect of introduction of air during the addition of pertechnetate as an example of poor labeling technique were examined. The radiochemical analyses were performed by paper and TL chromatography and electrophoresis.

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Journal of Radioanalytical and Nuclear Chemistry

Print ISSN:: 0236-5731

Online ISSN:: 1588-2780

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Journal of Radionalytical and Nuclear Chemistry
Language	English
Size	A4
Year of Foundation	1968
Volumes per Year	1
Issues per Year	12
Founder	Akadémiai Kiadó
Founder's Address	H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher	Akadémiai Kiadó Springer Nature Switzerland AG
Publisher's Address	H-1117 Budapest, Hungary 1516 Budapest, PO Box 245. CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible Publisher	Chief Executive Officer, Akadémiai Kiadó
ISSN	0236-5731 (Print)
ISSN	1588-2780 (Online)