Synthesis of195mPt radiolabeled cisdiammine (glycolato) platinum (II) of high radionuclidic purity

K. Kawai; Y. Tanaka; Y. Nakano; W. Ehrlich; M. Akaboshi

doi:10.1007/bf02162369

Jump to Content

Journal of Radioanalytical and Nuclear Chemistry

Volume/Issue:: Volume 199: Issue 3

Synthesis of^195mPt radiolabeled cisdiammine (glycolato) platinum (II) of high radionuclidic purity

Authors:

K. Kawai

K. Kawai Kyoto University Research Reactor Institute Kumatori-cho 590 Osaka Japan

Search for other papers by K. Kawai in
Current site
Google Scholar
PubMed

Y. Tanaka

Y. Tanaka Kyoto University Research Reactor Institute Kumatori-cho 590 Osaka Japan

Search for other papers by Y. Tanaka in
Current site
Google Scholar
PubMed

Y. Nakano

Y. Nakano Kyoto University Research Reactor Institute Kumatori-cho 590 Osaka Japan

Search for other papers by Y. Nakano in
Current site
Google Scholar
PubMed

W. Ehrlich

W. Ehrlich Robert Koch Institute D-1000 Berlin 65 Germany

Search for other papers by W. Ehrlich in
Current site
Google Scholar
PubMed

, and

M. Akaboshi

M. Akaboshi Kyoto University Research Reactor Institute Kumatori-cho 590 Osaka Japan

Search for other papers by M. Akaboshi in
Current site
Google Scholar
PubMed

View More View Less

Pages:: 207–215

Online Publication Date:: 27 Sep 2005

Publication Date:: 17 Feb 1995

Article Category:: Research Article

DOI:: https://doi.org/10.1007/bf02162369

Restricted access

Abstract

An experimental method is described for the synthesis of^195mPt-radiolabeled cis-diammine (glycolato) platinum (II) (254-S). Ten mg of 95% enriched¹⁹⁴Pt was irradiated for 75 h in the hydraulic conveyer of KUR at a thermal neutron flux of ca. 8.15×10¹³ n·cm^–2·s^–1, and the^195mPt-radiolabeled 254-S was synthesized and purified using HPLC (column: Dichrosorb Diol, elution: 80% CH₃CN). The chemical yield was approximately 45%, with chemical purity greater than 98.4%. The radionuclidic purity was nearly 100% and the specific activity, 7.2 MBq·mg^–1 254-S.

Save
Cite
Email this content

Share Link

Copy this link, or click below to email it to a friend
Email this content
or copy the link directly:

https://akjournals.com/abstract/journals/10967/199/3/article-p207.xml
The link was not copied. Your current browser may not support copying via this button.

Link copied successfully

Collapse
Expand

Journal of Radioanalytical and Nuclear Chemistry

Print ISSN:: 0236-5731

Online ISSN:: 1588-2780

To see the editorial board, please visit the website of Springer Nature.

Manuscript Submission: HERE

For subscription options, please visit the website of Springer Nature.

Journal of Radionalytical and Nuclear Chemistry
Language	English
Size	A4
Year of Foundation	1968
Volumes per Year	1
Issues per Year	12
Founder	Akadémiai Kiadó
Founder's Address	H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher	Akadémiai Kiadó Springer Nature Switzerland AG
Publisher's Address	H-1117 Budapest, Hungary 1516 Budapest, PO Box 245. CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible Publisher	Chief Executive Officer, Akadémiai Kiadó
ISSN	0236-5731 (Print)
ISSN	1588-2780 (Online)