Authors:
Yun-Zhong Liu Fu Wai Hospital CAMS Beijing (P.R. China)

Search for other papers by Yun-Zhong Liu in
Current site
Google Scholar
PubMed
Close
,
Lin Zhu National Research Center for CRM, S Beijing (P.R. China)

Search for other papers by Lin Zhu in
Current site
Google Scholar
PubMed
Close
,
Zheng Zhang Fu Wai Hospital CAMS Beijing (P.R. China)

Search for other papers by Zheng Zhang in
Current site
Google Scholar
PubMed
Close
,
Feng Guo Fu Wai Hospital CAMS Beijing (P.R. China)

Search for other papers by Feng Guo in
Current site
Google Scholar
PubMed
Close
, and
Xiu-Jie Liu Fu Wai Hospital CAMS Beijing (P.R. China)

Search for other papers by Xiu-Jie Liu in
Current site
Google Scholar
PubMed
Close
Restricted access

Abstract  

The biological behavior of Technetium-99m-L,L-Ethylenedicysteine (Tc-99m-EC)was compared with that of Technetium-99m-Mercaftoacetyltriglycine (Tc-99m-MAG3) and Iodine-131-hippuran (1131-OIH) in mice and rabbits. Tc-99m-EC showed a more rapid urinary excretion and less retention in kidney, liver, intestines and blood in comparison to Tc-99m-MAG3 and I-131-OIH. Urinary excretion decreased after probenecid treatment, indicating active tubular transport. In human bodies, the renal scintigraphy with Tc-99m-EC, Tc-99m-MAG3 and Tc-99m-DTPA were comparable. The promising results of the animal and human studies suggest that Tc-99m-EC may be a useful alternative to Tc-99m-MAG3 and I-131-OIH for renal functional studies.

  • Collapse
  • Expand

To see the editorial board, please visit the website of Springer Nature.

Manuscript Submission: HERE

For subscription options, please visit the website of Springer Nature.

Journal of Radionalytical and Nuclear Chemistry
Language English
Size A4
Year of
Foundation
1968
Volumes
per Year
1
Issues
per Year
12
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-5731 (Print)
ISSN 1588-2780 (Online)