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  • 1 University of Zurich and the Paul Scherrer Institute Institute for Medical Radiobiology of the CH-5232 Villigen-PSI Switzerland
  • 2 University Hospital Group Nuclear Chemistry and Radiopharmacy, Clinic for Nuclear Medicine D-45122 Essen Germany
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Abstract  

For more than a year,124I (T=4.15 d) has been produced routinely with a compact cyclotron by irradiation of124TeO2 with 14 MeV deuterons, followed by dry distillation of the iodine radioisotopes formed from irradiated target materials. The following by-products have been measured and compiled in each charge: 13.2-d123I, 60-d125I, 13.0-d126I, 12.4-h130I and 8.02-d131I. The data show that after 45 h decay time, the sum of the activities of these nuclides is less than 5% of the124I activity. Observation of this limit has been required by the Swiss Regulatory Agencies for a PET study of cell proliferation in human brain tumors using [124I] IUdR.