Authors:
R. Badiello Universitŕ di Bologna Unitr Complessa di Scienze Chimiche, Radiochimiche e Metallurgiche Bologna Italy

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G. Ceschel Universitŕ di Bologna Dipartimento di Scienze Farmaceutiche Bologna Italy

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B. Esposito Universitŕ di Bologna Unitr Complessa di Scienze Chimiche, Radiochimiche e Metallurgiche Bologna Italy

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Abstract  

The paper investigates the effect of glutathione on model biological systems, such as enzymes, (lisozyme, alcoholdehydrogenase, α-chymotrypsin) and DNA base components. Our results on the inactivation of enzymes and on the chemical changes in DNA base components show a radioprotective action of glutathione in all systems. The results are discussed in terms of glutathione free radical reactivity and in the light of current hypothesis on the modification of the radiation damage given by thiol compounds.

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Journal of Radionalytical and Nuclear Chemistry
Language English
Size A4
Year of
Foundation
1968
Volumes
per Year
1
Issues
per Year
12
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-5731 (Print)
ISSN 1588-2780 (Online)