Authors:
S. Oishi Kanazawa University School of Health Sciences, Faculty of Medicine 920-0942 Kanazawa, Ishikawa Japan

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R. Amano Kanazawa University School of Health Sciences, Faculty of Medicine 920-0942 Kanazawa, Ishikawa Japan

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A. Ando Kanazawa University School of Health Sciences, Faculty of Medicine 920-0942 Kanazawa, Ishikawa Japan

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S. Enomoto The Institute of Physical and Chemical Research (RIKEN) 351-0198 Wako, Saitama Japan

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F. Ambe The Institute of Physical and Chemical Research (RIKEN) 351-0198 Wako, Saitama Japan

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Abstract  

The radioactive multitracer technique was applied to a study on the uptake of trace elements in normal C57BL/6N mice. Comparative uptake behavior of46Sc,54Mn,59Fe,58Co,65Se,83Rb and88Zr tracers was examined among 11 organs (brain, cardiac muscle, lung, liver, spleen, pancreas, kidneys, bone, muscle, eyeballs and testes) and blood, and evaluated in terms of the “tissue uptake rate (the radioactivity percentage of injected dose per gram of tissue, %dose/g)”. The multitracer technique revealed reliable data demonstrating characteristic uptake of the 8 trace elements, Sc, Mn, Fe, Co, Zn, Se, Rb and Zr by the brain and other organs, as well as the distinctive features of the accumulation and retention of each element in the brain.

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Journal of Radionalytical and Nuclear Chemistry
Language English
Size A4
Year of
Foundation
1968
Volumes
per Year
1
Issues
per Year
12
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-5731 (Print)
ISSN 1588-2780 (Online)