Authors:
F. Lambert Centre d'Etudes Nucléaires de Saclay Laboratoire de Contrôle Pharmaceutique. Département des Radioéléments Gif-sur-Yvette (France)

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P. Frapart Centre d'Etudes Nucléaires de Saclay Laboratoire de Contrôle Pharmaceutique. Département des Radioéléments Gif-sur-Yvette (France)

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Y. Cohen Centre d'Etudes Nucléaires de Saclay Laboratoire de Contrôle Pharmaceutique. Département des Radioéléments Gif-sur-Yvette (France)

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Abstract  

Pulse radiolysis of MIT and DIT irradiated to doses from 2.8·104 to 85·104 rads is studied by ascending chromatography. The 3-iodo-4,5-dihydroxyphenylalanine (DOPA-I) and 3-iodo-4-hydroxyphenylalanine have been identified as first stages of degradations of MIT and DIT, respectively. G values are 0.015 for MIT (10−5M) and 0.004 for DIT (0.5·10−5M). By self decomposition MIT is degraded less rapidly than DIT and there is no formation of DOPA-I.

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Journal of Radionalytical and Nuclear Chemistry
Language English
Size A4
Year of
Foundation
1968
Volumes
per Year
1
Issues
per Year
12
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-5731 (Print)
ISSN 1588-2780 (Online)