Journal of Radioanalytical and Nuclear Chemistry
Volume/Issue:
Volume 240: Issue 2
Myocardial reversibility detection. Rest NTG99mTc-MIBI versus201TI reinjection. Preliminary results
Authors:
O. Pereztol Center for Clinical Researches Calle 34# 4501 e/ 45 y 47, Rpto Kolhy, Playa Havana Cuba

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J. Batista Center for Clinical Researches Calle 34# 4501 e/ 45 y 47, Rpto Kolhy, Playa Havana Cuba

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J. Valdés Center for Clinical Researches Calle 34# 4501 e/ 45 y 47, Rpto Kolhy, Playa Havana Cuba

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L. Rochela Center for Clinical Researches Calle 34# 4501 e/ 45 y 47, Rpto Kolhy, Playa Havana Cuba

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F. Sosa Center for Clinical Researches Calle 34# 4501 e/ 45 y 47, Rpto Kolhy, Playa Havana Cuba

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D. López Center for Clinical Researches Calle 34# 4501 e/ 45 y 47, Rpto Kolhy, Playa Havana Cuba

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E. Sánchez Center for Clinical Researches Calle 34# 4501 e/ 45 y 47, Rpto Kolhy, Playa Havana Cuba

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B. Pérez Center for Clinical Researches Calle 34# 4501 e/ 45 y 47, Rpto Kolhy, Playa Havana Cuba

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Pages:
489–497
Online Publication Date:
10 Apr 2006
Publication Date:
17 May 1999
Article Category:
Research Article
DOI:
https://doi.org/10.1007/bf02349401
Restricted access

Abstract  

This study test whether sublingual administration of nitroglycerin (NTG) could improve the capability of99mTc-MIBI to detect reversibility in exercise-induced perfusion defects and to compare it with the201TI stress-redistribution-reinjection protocol. Twenty-one patients with previous myocardial infarction were submitted to exercise, rest and NTG rest99mTc-MIBI imaging (3-day protocol). The patients also underwent exercise, redistribution and reinjection201Tl myocardial scintigraphy. A total of 273 myocardial segments were analyzed: 76 (28%) had irreversible defects on stress-rest99mTc-MIBI, 60 (79%) appeared as fixed defects and 16 (21%) were reversible on NTG rest99mTc-MIBI. Of the 78 myocardial segments with irreversible defects on standard stress-redistribution thallium cardiac imaging, 63 (81%) did not change and 15 (19%) demonstrated enhanced uptake of thallium after reinjection. Data show that rest NTG99mTc-MIBI study improves the detection of reversible myocardium versus standard exercise/rest99mTc-MIBI and achieve similar results than201Tl reinjection protocol.

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Cover Journal of Radioanalytical and Nuclear Chemistry
Journal of Radioanalytical and Nuclear Chemistry
Print ISSN:
0236-5731
Online ISSN:
1588-2780

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Journal of Radionalytical and Nuclear Chemistry
Language English
Size A4
Year of
Foundation		 1968
Volumes
per Year		 1
Issues
per Year		 12
Founder Akadémiai Kiadó
Founder's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher		 Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-5731 (Print)
ISSN 1588-2780 (Online)

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