Authors:
S. Zeisler German Cancer Research Centre, Department of Radiochemistry im Neuenheimer Feld 280 D-69120 Heidelberg Germany

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D. Becker German Cancer Research Centre, Department of Radiochemistry im Neuenheimer Feld 280 D-69120 Heidelberg Germany

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K. Weber German Cancer Research Centre, Department of Radiochemistry im Neuenheimer Feld 280 D-69120 Heidelberg Germany

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Abstract  

The β-emitting isotope142gPr (T1/2=19.13 h, E(β)max=2.16 MeV) is a suitable radionuclide for internal radiotherapy with tumor-seeking biomolecules.142gPr can be prepared from natural141Pr by irradiation with thermal neutrons. We investigated the Szilard-Chalmers reaction in well-defined complexes with various ligands and a salt in order to measure the enrichment factors and extracted yields to find a route for the production142gPr of high specific radioactivity, ionic142gPr3+ was separated from the complex by cation exchange and high performance liquid chromatography (HPLC).

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Journal of Radionalytical and Nuclear Chemistry
Language English
Size A4
Year of
Foundation
1968
Volumes
per Year
1
Issues
per Year
12
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-5731 (Print)
ISSN 1588-2780 (Online)