Authors:
T. Kniess Institut für Bioanorganische und Radiopharmazeutische Chemie Forschungszentrum Rossendorf P.O. Box 51 01 19 D-01314 Dresden Germany

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S. Noll Institut für Bioanorganische und Radiopharmazeutische Chemie Forschungszentrum Rossendorf P.O. Box 51 01 19 D-01314 Dresden Germany

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B. Noll Institut für Bioanorganische und Radiopharmazeutische Chemie Forschungszentrum Rossendorf P.O. Box 51 01 19 D-01314 Dresden Germany

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H. Spies Institut für Bioanorganische und Radiopharmazeutische Chemie Forschungszentrum Rossendorf P.O. Box 51 01 19 D-01314 Dresden Germany

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B. Johannsen Institut für Bioanorganische und Radiopharmazeutische Chemie Forschungszentrum Rossendorf P.O. Box 51 01 19 D-01314 Dresden Germany

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Abstract  

The coupling of Re- and99mTc-MAG3 complexes with amines and nucleobases was carried out with good yields using O-(benzotriazol-1-yl-)-N,N,N',N'-tetramethyl-uronium-tetrafluoroborate (TBTU), and base in polar aprotic solvents (NMP, DMF, DMSO). The one step reaction followed by simple gel chromatography makes the method well appropriate for preparations at the low no-carrier-added level of technetium-99m.

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Journal of Radionalytical and Nuclear Chemistry
Language English
Size A4
Year of
Foundation
1968
Volumes
per Year
1
Issues
per Year
12
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-5731 (Print)
ISSN 1588-2780 (Online)