Authors:
I. StamatelatosNCSR “Demokritos” Institute of Nuclear Technology and Radiation Protection Aghia Paraskevi 153 10 Greece

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K. KatopodisUniversity of Ioannina Department of Internal Medicine, Division of Nephrology 451 10 Ioannina Greece

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Y. BersosSismanoglio Hospital Clinical Chemistry Laboratory 151 26 Maroussi Greece

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J. Kalef-EzraUniversity of Ioannina Medical Physics Laboratory, Medical School 451 10 Ioannina Greece

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G. LefkopoulosNCSR “Demokritos” Institute of Nuclear Technology and Radiation Protection Aghia Paraskevi 153 10 Greece

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K. SiamopoulosUniversity of Ioannina Department of Internal Medicine, Division of Nephrology 451 10 Ioannina Greece

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Abstract  

Serum aluminum levels were determined by instrumental neutron activation analysis in 31 patients undergoing long-term haemodialysis. Aluminum-28 1.778 MeV (T1/2=2.24 min) γ-rays produced by the thermal neutron reaction27Al(n,γ)28Al were detected. Successive irradiation of the samples at epithermal neutron fluence was performed to correct for the interference from the fast neutron reaction31P(n,α)28Al. Serum aluminum level in this group of subjects was adequately represented by a lognormal distribution with a mean and variance of 16.5 μg/l and 16.8 μg/l, respectively. The results obtained were found to be in agreement with serum aluminum determination performed by electrothermal atomic absorption spectrophotometry (r2=0.97). Instrumental neutron activation can provide a rapid technique to routinely monitor long-term haemodialysis patients in order to identify individuals at greater risk to develop aluminum toxicity.

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Journal of Radionalytical and Nuclear Chemistry
Language English
Size A4
Year of
Foundation
1968
Volumes
per Year
1
Issues
per Year
12
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-5731 (Print)
ISSN 1588-2780 (Online)