Authors:
A. Mushtaq Pakistan Institute of Nuclear Science and Technology Radioisotope Production Group, Nuclear Chemistry Division P.O. Nilore Islamabad Pakistan

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Sh. Pervez Pakistan Institute of Nuclear Science and Technology Radioisotope Production Group, Nuclear Chemistry Division P.O. Nilore Islamabad Pakistan

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I. Haider Pakistan Institute of Nuclear Science and Technology Radioisotope Production Group, Nuclear Chemistry Division P.O. Nilore Islamabad Pakistan

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M. Mansur Pakistan Institute of Nuclear Science and Technology Radioisotope Production Group, Nuclear Chemistry Division P.O. Nilore Islamabad Pakistan

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M. Jehangir Pakistan Institute of Nuclear Science and Technology Radioisotope Production Group, Nuclear Chemistry Division P.O. Nilore Islamabad Pakistan

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Abstract  

99mTc pentavalent dimercaptosuccinic acid [99mTc(V) DMSA], a useful agent for imaging thyroid medullary carcinoma and other tumors can be reliably prepared by addition of Na99mTcO4 to a freeze-dried mixture of DMSA and Sn (2:1 molar ratio). The radiochemical purity, stability and animal bio-distribution behaviour is similar to that of the agent made by addition of NaHCO3 to DMSA (III) renal imaging freeze-dried kit.

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Journal of Radionalytical and Nuclear Chemistry
Language English
Size A4
Year of
Foundation
1968
Volumes
per Year
1
Issues
per Year
12
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-5731 (Print)
ISSN 1588-2780 (Online)