Authors:
M. Bonardi Universita' degli Studi and INFN Accelerators and Applied Superconductivity Laboratory, LASA, Radiochemistry Laboratory Via F.lli Cervi 201 I-20090 Segrate, Milano Italy

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F. Groppi Universita' degli Studi and INFN Accelerators and Applied Superconductivity Laboratory, LASA, Radiochemistry Laboratory Via F.lli Cervi 201 I-20090 Segrate, Milano Italy

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C. Birattari Universita' degli Studi and INFN Accelerators and Applied Superconductivity Laboratory, LASA, Radiochemistry Laboratory Via F.lli Cervi 201 I-20090 Segrate, Milano Italy

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L. Gini Universita' degli Studi and INFN Accelerators and Applied Superconductivity Laboratory, LASA, Radiochemistry Laboratory Via F.lli Cervi 201 I-20090 Segrate, Milano Italy

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C. Mainardi Universita' degli Studi and INFN Accelerators and Applied Superconductivity Laboratory, LASA, Radiochemistry Laboratory Via F.lli Cervi 201 I-20090 Segrate, Milano Italy

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A. Ghioni Universita' degli Studi and INFN Accelerators and Applied Superconductivity Laboratory, LASA, Radiochemistry Laboratory Via F.lli Cervi 201 I-20090 Segrate, Milano Italy

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E. Menapace Division for Advanced Physical Technologies Via Don Fiammelli, 2 I-40128 Bologna Italy

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K. Abbas European Communities Institute for Health and Consumer Protection, IHCP, JRC, Ispra Via E. Fermi 1 I-21020 Varese Italy

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U. Holzwarth European Communities Institute for Health and Consumer Protection, IHCP, JRC, Ispra Via E. Fermi 1 I-21020 Varese Italy

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M. Stroosnijder European Communities Institute for Health and Consumer Protection, IHCP, JRC, Ispra Via E. Fermi 1 I-21020 Varese Italy

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Abstract  

Copper-64 is a radionuclide suitable for labeling of a wide range of radiopharmaceuticals for PET imaging, as well as systemic or local radioimmunotherapy of tumors. Among the possible methods for cyclotron production of No Carrier Added (NCA) 64Cu (61Cu), we investigated the deuteron irradiation on natural Zn target, via (d,axn) and (d,2pxn) nuclear reactions. This paper reports the preliminary results about the experimental determination and theoretical calculation of thin-target excitation functions in the energy range up to 19 MeV for 61Cu, 64Cu, 66Ga, 67Ga, 65Zn and 69mZn. A fast selective radiochemical separation of NCA 64Cu from Zn target and Ga radionuclides, with quality control tests is described too.

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Journal of Radionalytical and Nuclear Chemistry
Language English
Size A4
Year of
Foundation
1968
Volumes
per Year
1
Issues
per Year
12
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-5731 (Print)
ISSN 1588-2780 (Online)