Authors:
H. Oudadesse Université de Rennes 1 Institut de Chimie de Rennes, Laboratoire Chimie du Solide et Inorganique Moléculaire, CNRS-UMR 6511-Cristallochimie et Biomatériaux CS 74205, Campus de Beaulieu, Bât 10B 35042 Rennes Cedex France E-mail

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S. Martin Université de Rennes 1 UFR Odontologie, Biomatériaux en site osseux 5 rue Pasteur 3500 Rennes Cedex France

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A. Derrien Université de Rennes 1 Institut de Chimie de Rennes, Laboratoire Chimie du Solide et Inorganique Moléculaire, CNRS-UMR 6511-Cristallochimie et Biomatériaux CS 74205, Campus de Beaulieu, Bât 10B 35042 Rennes Cedex France E-mail

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A. Lucas-Girot Université de Rennes 1 Institut de Chimie de Rennes, Laboratoire Chimie du Solide et Inorganique Moléculaire, CNRS-UMR 6511-Cristallochimie et Biomatériaux CS 74205, Campus de Beaulieu, Bât 10B 35042 Rennes Cedex France E-mail

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G. Cathelineau Université de Rennes 1 UFR Odontologie, Biomatériaux en site osseux 5 rue Pasteur 3500 Rennes Cedex France

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G. Blondiaux Centre d'Etudes et de Recherche par Irradiation CNRS-CERI 3A, Rue de la ferollerie 45071 Orléans France

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Abstract  

In orthopaedic surgery, synthetic biomaterials encountered a great success. In this work, the “in-vivo” behaviour of aragonite synthesized in our laboratory was studied. The in vivo experiments have been carried out on femurs sites of nine ovine. Neutron activation analysis was applied to evaluate the ossification kinetics of synthetic aragonite. The content of several elements (Ca, P, Sr and Mg and phosphorous to calcium ratio) were determined versus time after implantation. Results showed that the biomaterial undergoes a lot of transformations during time. The chemical composition of the aragonite was modified and progress to become close to that of an ovine bone. Biological studies assess its biocompatibility.

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Journal of Radionalytical and Nuclear Chemistry
Language English
Size A4
Year of
Foundation
1968
Volumes
per Year
1
Issues
per Year
12
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-5731 (Print)
ISSN 1588-2780 (Online)