A bilirubin-chloroform solution was tested as a gamma-radiation dosimeter (SALPILL dosimeter) in the 0-100 Gy range, and at dose rates between 0.01 to 3.18 Gy . min-1, which displayed certain advantages over the conventional Fricke, TLD and diode dosimeters when examined under identical experimental conditions. The principle of operation involved gamma-irradiation of micro-molar quantities of the unconjugated specimen with a 137Cs source (662 keV gamma-rays), and measurement of the (degraded) bilirubin absorption at 453 nm. The relationship of bilirubin depletion and radiation dose was linear, which remained invariant with oxic and anoxic exposure, denoting excellent reproducibility under diverse experimental conditions. Further validation of performance was achieved by repeated in-air trials, which produced a reproducibility within ±2% (n = 5). Stringent comparative tests conducted against currently accepted gamma-radiation dosimeters favoured the SALPILL dosimeter in all the relevant areas. The merits of using chloroform as a solvent in place of water was considered. The SALPILL dosimeter has the following distinctive features: prolonged “shelf-life” (before and after irradiation), insensitive into oxygen, operational at relatively low dose rates, linear functionality at low doses (0-5 Gy), solvent stability, solute integrity, reliability, convenient and cost-effective. The drawbacks of SALPILL are minimal, which makes it a facile dosimeter for certain applications.