82Rb is a generator produced positron-emitting isotope (T1/2 = 75 s) that is increasingly being used in positron emission tomography for the characterization of myocardial perfusion. The parent radionuclide of 82Rb, strontium 82Sr, is produced mainly by a (p, 4n) reaction induced by >40 MeV protons on rubidium (85Rb) target. In the present work we propose a new fast and simple procedure for 82Sr separation from the target, based on selective adsorption of rubidium on the inorganic ion-exchanger: cryptomelane MnO2.