The distribution coefficients of204Tl(III) between DEAE-cellulose and HCl-water-organic solvent (alcohols and ketones) mixtures have been determined using the statical method. The hydrochloric acid concentration as well as the nature and concentration of organic solvent in the mixtures have been widely varied. Sorption of Tl(III) takes place through a combined process of ion exchange and physical adsorption, its distribution between the anionic cellulose and solvent mixture depends on the tendency of the ionic association formation in these media.