Journal of Radioanalytical and Nuclear Chemistry
Volume/Issue:
Volume 271: Issue 2
A technique for the determination of ruthenium stable isotopes in urine samples
Authors:
I. Veronese

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M. Cantone

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A. Giussani

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A. Arogunjo Università degli Studi di Milano Dipartimento di Fisica Italy

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P. Roth GSF, National Research Center for Environment and Health Institute of Radiation Protection Ingolstädter Landstraße 1 D-85764 Neuherberg Germany

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V. Höllriegl GSF, National Research Center for Environment and Health Institute of Radiation Protection Ingolstädter Landstraße 1 D-85764 Neuherberg Germany

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U. Oeh GSF, National Research Center for Environment and Health Institute of Radiation Protection Ingolstädter Landstraße 1 D-85764 Neuherberg Germany

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U. Holzwarth Joint Research Centre of the European Commission Institute for Health and Consumer Protection Via Fermi I-21020 Ispra (Va) Italy

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K. Abbas Joint Research Centre of the European Commission Institute for Health and Consumer Protection Via Fermi I-21020 Ispra (Va) Italy

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Pages:
497–501
Online Publication Date:
06 Dec 2006
Publication Date:
01 Feb 2007
Article Category:
Research Article
DOI:
https://doi.org/10.1007/s10967-007-0236-8
Restricted access

Abstract  

Proton activation analysis has been recently applied for the determination of stable isotopes of trace metals in blood plasma samples taken from volunteers during tracer kinetic studies. The very low values of intestinal uptake for some elements, like ruthenium, make the kinetics of the excretion crucial for interpreting the bioassay data. Therefore, a procedure has been developed to process urine samples in order to have proper targets for the activation with protons. Preliminary tests with Ru-doped samples, conducted using the MC-40 Cyclotron at JRC Ispra, has confirmed the feasibility of the method. The minimum detectable concentrations, in the current operating conditions, are 16 ng 99Ru·ml−1 and 0.5 ng 101Ru·ml−1.

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Cover Journal of Radioanalytical and Nuclear Chemistry
Journal of Radioanalytical and Nuclear Chemistry
Print ISSN:
0236-5731
Online ISSN:
1588-2780

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Journal of Radionalytical and Nuclear Chemistry
Language English
Size A4
Year of
Foundation		 1968
Volumes
per Year		 1
Issues
per Year		 12
Founder Akadémiai Kiadó
Founder's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher		 Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-5731 (Print)
ISSN 1588-2780 (Online)

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