Journal of Radioanalytical and Nuclear Chemistry
Volume/Issue:
Volume 272: Issue 2
Element distribution in the brain of rats exposed to lanthanum measured by synchrotron radiation X-ray fluorescence
Authors:
L. Feng

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H. Xiao Chinese Academy of Sciences Key Laboratory of Nuclear Analytical Techniques, Institute of High Energy Physics Beijing 100049 P.R. China

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X. He

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Z. Li

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F. Li Chinese Academy of Sciences Key Laboratory of Nuclear Analytical Techniques, Institute of High Energy Physics Beijing 100049 P.R. China

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N. Liu Chinese Academy of Sciences Key Laboratory of Nuclear Analytical Techniques, Institute of High Energy Physics Beijing 100049 P.R. China

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Z. Chai

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Y. Zhao Chinese Academy of Sciences Key Laboratory of Nuclear Analytical Techniques, Institute of High Energy Physics Beijing 100049 P.R. China

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Y. Huang Shenzhen University Institute of Nuclear Technology Shenzhen 518060 P.R. China

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W. He Shenzhen University Institute of Nuclear Technology Shenzhen 518060 P.R. China

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Z. Zhang Chinese Academy of Sciences Key Laboratory of Nuclear Analytical Techniques, Institute of High Energy Physics Beijing 100049 P.R. China

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Pages:
333–337
Online Publication Date:
27 Feb 2007
Publication Date:
01 May 2007
Article Category:
Research Article
DOI:
https://doi.org/10.1007/s10967-007-0525-2
Restricted access

Abstract  

To investigate the effects of lanthanum exposure on regional distribution of inorganic elements in rat brain. Wistar rats were exposed to lanthanum chloride through oral administration at 0, 0.1, 2, and 40 mg/kg concentration for 6 months. The elements such as Cl, K, Ca, Fe, Cu, and Zn were identified in the brain slices by synchrotron radiation X-ray fluorescence (SRXRF) analysis. Differences of brain elemental distributions were noticed. Cl, Ca, and Zn were primarily concentrated in hippocampus of the controls. With the increase of the lanthanum dosage, the Ca and Zn levels significantly decreased, while the Cu levels significantly elevated in cortex, hippocampus and thalamus. Our results suggest that subchronic lanthanum exposure in rats appears to change elemental distributions in brain.

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Cover Journal of Radioanalytical and Nuclear Chemistry
Journal of Radioanalytical and Nuclear Chemistry
Print ISSN:
0236-5731
Online ISSN:
1588-2780

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Journal of Radionalytical and Nuclear Chemistry
Language English
Size A4
Year of
Foundation		 1968
Volumes
per Year		 1
Issues
per Year		 12
Founder Akadémiai Kiadó
Founder's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address		 H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher		 Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-5731 (Print)
ISSN 1588-2780 (Online)

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