In the boron neutron capture therapy, an accurate determination of the boron content in a biological sample is very important.
The boron content was investigated with a standard solution of boron which was administered intraperitoneally with a dose
of 750 mg/kg body weight into mice induced cancer cells and tumors. The boron content for two types of a sample was compared
to the boronophenylalanine for the tumor and the ethylamine derivatives for the induced cancer cell, which were also investigated
for their accumulation rate in each organ such as blood, spleen, liver, kidney and brain. An analytical quality control was
carried out by using certified reference materials such as Peach Leaves, Apple Leaves and Spinach Leaves. The relative error
of the measured values was in good agreement within 2% to the certified values.