Effects of acute lanthanum exposure on calcium absorption in rats

X. He; Z. Zhang; L. Feng; Z. Li; J. Yang; Y. Zhao; Z. Chai

doi:10.1007/s10967-007-0623-1

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Journal of Radioanalytical and Nuclear Chemistry

Volume/Issue:: Volume 272: Issue 3

Effects of acute lanthanum exposure on calcium absorption in rats

Authors:

X. He

X. He

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Z. Zhang

Z. Zhang Chinese Academy of Sciences Key Laboratory of Nuclear Analytical Techniques, Institute of High Energy Physics Beijing 100049 P.R. China

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L. Feng

L. Feng

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Z. Li

Z. Li

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J. Yang

J. Yang Chinese Academy of Sciences Key Laboratory of Nuclear Analytical Techniques, Institute of High Energy Physics Beijing 100049 P.R. China

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Y. Zhao

Y. Zhao Chinese Academy of Sciences Key Laboratory of Nuclear Analytical Techniques, Institute of High Energy Physics Beijing 100049 P.R. China

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Z. Chai

Z. Chai

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Pages:: 557–559

Online Publication Date:: 08 Mar 2007

Publication Date:: 01 Jun 2007

Article Category:: Research Article

DOI:: https://doi.org/10.1007/s10967-007-0623-1

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Abstract

After an acute exposure to lanthanum chloride, the pharmacokinetics of calcium uptake in rats was studied by radioactive ⁴⁷Ca tracer. The accumulated doses of calcium in the left femurs during 24 hours were determined. The results showed that the area under the curves (AUC), specific activity of maximal blood ⁴⁷Ca concentration (C_max), distribution rate constant (K_a) and the accumulated dose of calcium in the left femur decreased while time to C_max (T_peak) increased with the rising dosage of lanthanum exposure. It indicated that lanthanum expose had a negative effect on calcium absorption.

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Journal of Radioanalytical and Nuclear Chemistry

Print ISSN:: 0236-5731

Online ISSN:: 1588-2780

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Journal of Radionalytical and Nuclear Chemistry
Language	English
Size	A4
Year of Foundation	1968
Volumes per Year	1
Issues per Year	12
Founder	Akadémiai Kiadó
Founder's Address	H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher	Akadémiai Kiadó Springer Nature Switzerland AG
Publisher's Address	H-1117 Budapest, Hungary 1516 Budapest, PO Box 245. CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible Publisher	Chief Executive Officer, Akadémiai Kiadó
ISSN	0236-5731 (Print)
ISSN	1588-2780 (Online)