The interaction of the clinically used 1,2-dimethyl-3-hydroxypyrid-4-one with trivalent europium Eu(III), was investigated
by using potentiometric and spectroscopic methods. The stability constants of the EuLn(3−n)+ complexes determined by spectroscopic and potentiometric measurements were found to be log β11 = 6.5±0.3 and log β12 = 12.0±0.5. However, at pH ≥ 5, hydrolysis of the Eu-L complexes starts, resulting in the formation of needle-type, yellow
crystals. The low solubility of the Eu-L complexes in the neutral pH range is disadvantageous with respect to the use of deferiprone
as chelating agent for decorporation of trivalent f-elements.