Authors:
Le Van So Australian Nuclear Science and Technology Organisation Radiopharmaceutical Research Institute New Illawarra Road, Lucas Heights, P.M.B 1 Menai NSW 2234 Australia

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P. Pellegrini Australian Nuclear Science and Technology Organisation Radiopharmaceutical Research Institute New Illawarra Road, Lucas Heights, P.M.B 1 Menai NSW 2234 Australia

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A. Katsifis Australian Nuclear Science and Technology Organisation Radiopharmaceutical Research Institute New Illawarra Road, Lucas Heights, P.M.B 1 Menai NSW 2234 Australia

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J. Howse Australian Nuclear Science and Technology Organisation Radiopharmaceutical Research Institute New Illawarra Road, Lucas Heights, P.M.B 1 Menai NSW 2234 Australia

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I. Greguric Australian Nuclear Science and Technology Organisation Radiopharmaceutical Research Institute New Illawarra Road, Lucas Heights, P.M.B 1 Menai NSW 2234 Australia

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Abstract  

The radiochemical separation of the different radionuclides (64Cu, 67Cu, 67Ga, 66Ga, 56Ni, 57Ni, 55Co, 56Co, 57Co, 65Zn, 196Au) induced in the Ni supported Cu substrate — 68Zn target system, which was bombarded with the 29.0 MeV proton beam, was performed by ion-exchange chromatography using successive isocratic and/or concentration gradient elution techniques. The overlapped gamma-ray spectrum analysis method was developed to assess the 67Ga and 67Cu content in the 64Cu product and even in the post-67Ga production 68Zn target solution without the support of radiochemical separation. This method was used for the assessment of 64+67Cu radioisotope separation from 67Ga, the quality control of 64Cu product and the determination of the 68Zn (p,2p)67Cu reaction yield. The improvement in the targetry and the optimization of proton beam energy for the 68Zn target based 64Cu and 67Ga production were proposed based on the stopping power and range of the incident proton and on the excitation functions, reaction yields and different radionuclides induced in the target system.

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Journal of Radionalytical and Nuclear Chemistry
Language English
Size A4
Year of
Foundation
1968
Volumes
per Year
1
Issues
per Year
12
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-5731 (Print)
ISSN 1588-2780 (Online)