The k0-IAEA program developed for implementation of the single comparator instrumental neutron activation analysis method (k0-INAA) has been used for elemental analysis with NIRR-1 irradiation and counting facilities. The existing experimental protocols
for routine analysis based on the relative method were used to test the capability and reliability of the program for the
analyses of geological and biological samples. The Synthetic Multi-element Standards (SMELS) types I, II and III recommended
by the international k0 user community for the validation of k0-NAA method in NAA laboratories, furthermore, the following standard reference materials: NIST-1633b (Coal Fly Ash) and IAEA-336
(Lichen) were analyzed. Results obtained with the version 3.12 of the k0-IAEA program were found to be in good agreement with the data obtained with the established relative method using WINSPAN-2004
software. Detection limits for elemental analysis of geological and biological samples with NIRR-1 facilities are provided.