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  • 1 Department of Medical Radiation Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran
  • | 2 Agricultural, Medical and Industrial Research School, Nuclear Science and Technology Research Institute, P.O. Box 31485/498, Karaj, Tehran, Iran
  • | 3 Department of Energy Science, Sungkyunkwan University, 300 Cheongcheon-dong, Suwon, Korea
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Abstract  

Application of nanoparticles in nuclear medicine has aimed to develop diagnosis and therapeutic techniques. Cerium oxide nanoparticles (CNPs) are expected to be useful for protection of healthy tissue from radiation-induced harm and could serve therapeutic function. Among a variety of cerium radioisotopes, 137mCe (T1/2 = 34.4 h, IT (99.22%), β+ (0.779%)) could be a novel candidate radionuclide in the field of diagnosis owing to its appropriate half-life, 99.91% natural abundance of target and its intense gamma line at 254.29 keV. In this study, 137mCe excitation function via the natLa(p,3n) reaction was calculated by TALYS-1.2 and EMPIRE-3 codes. The excitation function calculations demonstrated that the natLa(p,3n)137mCe reaction leads to the formation of the 136/138Ce isotopic contamination in the 22–35 MeV energy range. Interestingly, the isotopic impurities of 137mCe could serve radio protector function. Overall results indicate that the cyclotron produced 137mCeO2 nanoparticles by irradiation of a target encompassing lanthanum oxide nanoparticles could be a potent alternative for conventional diagnostic radionuclides with simultaneous radioprotection capacity.

Manuscript Submission: HERE

  • Impact Factor (2019): 1.137
  • Scimago Journal Rank (2019): 0.360
  • SJR Hirsch-Index (2019): 65
  • SJR Quartile Score (2019): Q3 Analytical Chemistry
  • SJR Quartile Score (2019): Q3 Health, Toxicology and Mutagenesis
  • SJR Quartile Score (2019): Q2 Nuclear Energy and Engineering
  • SJR Quartile Score (2019): Q3 Pollution
  • SJR Quartile Score (2019): Q3 Public Health, Environmental and Occupational Health
  • SJR Quartile Score (2019): Q3 Radiology, Nuclear Medicine and Imaging
  • SJR Quartile Score (2019): Q3 Spectroscopy
  • Impact Factor (2018): 1.186
  • Scimago Journal Rank (2018): 0.408
  • SJR Hirsch-Index (2018): 60
  • SJR Quartile Score (2018): Q2 Nuclear Energy and Engineering
  • SJR Quartile Score (2018): Q2 Pollution

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Journal of Radionalytical and Nuclear Chemistry
Language English
Size A4
Year of
Foundation
1968
Volumes
per Year
4
Issues
per Year
12
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-5731 (Print)
ISSN 1588-2780 (Online)