The applications of a conventional 2.5 MeV Van de Graaff machine for analytical work using a beam of accelerated protons or deuterons is described. These applications include (1) the depth concentration of deuterium in steels using a nuclear reaction technique, (2) the location of3He atoms in the erbium hydride lattice using ion channelling and (3) the identification of vanadium oxides formed by sputtering using Rutherford backscattering and electron diffraction. Provisional results are presented.