The detection limits of many nonnuclear methods for ultratrace (≤0.1 μg/g) elemental determinations lie well below the level
at which precise and accurate practical analysis can be executed routinely. Advances in analytical methodologies which are
rapidly eroding such disparities are reviewed. The applications of X-ray fluorescence, atomic absorption, stable isotope dilution
mass spectrometry, and laser intracavity absorption spectrophotometry to ultratrace analyses not amenable to solution by nuclear
methods are discussed.