Authors:
S. Ohmori Osaka Prefectural Institute of Public Health 1-3-69, Higashinari-ku 537 Osaka (Japan)

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K. Hashimoto Kanazawa University Department of Hygiene, School of Medicine 920 Kanazawa (Japan)

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Abstract  

For the purpose of studying the secretion of exogenous toxic metals into hair, relation between their concentrations in hair and those in organs, and the metal shift, Hg or Mn was orally administered to guinea pigs for protracted periods, the distributions of metals in hair and organs were examined by means of neutron activation analysis. It was found that the administration of Hg at high dose resulted in abnormally high Hg levels in hair from the 2nd dosing week and in organs after 25 week dosing, and in a reduced motor activity after 25 week administration. There occurred metal shifts in hair as well. Administration of Mn at high doses, on the other hand, showed no such biological influences, although a dose-dependent increase of Mn in hair was detected with time.

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Journal of Radionalytical and Nuclear Chemistry
Language English
Size A4
Year of
Foundation
1968
Volumes
per Year
1
Issues
per Year
12
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-5731 (Print)
ISSN 1588-2780 (Online)