Authors:
M. Goodman Oak Ridge National Laboratory Nuclear Medicine Group 37830 Oak Ridge Tennessee (USA)

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F. Knapp Oak Ridge National Laboratory Nuclear Medicine Group 37830 Oak Ridge Tennessee (USA)

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P. Richards Brookhaven National Laboratory Medical Department Upton New York (USA)

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F. Mausner Brookhaven National Laboratory Medical Department Upton New York (USA)

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Abstract  

The triazene derivative of 15-(p-aminophenyl)pentadecanoic acid, 1-[4-(15-oxopentadecanoyl)phenyl]-3,3-(1,5-pentanediyl)triazene, has been sythesized as a new substrate which is readily converted to 15-(p-iodophenyl)-pentadecanoic acid (IPP). Iodine-123-labeled IPP is prepared in 30% yield in less than 30 min by reaction of the triazene with no-carrier added H123I, obtained by decay of123Xe. This rapid, regiospecific synthesis represents as improved method for the preparation of [123I]IPP.

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Journal of Radionalytical and Nuclear Chemistry
Language English
Size A4
Year of
Foundation
1968
Volumes
per Year
1
Issues
per Year
12
Founder Akadémiai Kiadó
Founder's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
Publisher Akadémiai Kiadó
Springer Nature Switzerland AG
Publisher's
Address
H-1117 Budapest, Hungary 1516 Budapest, PO Box 245.
CH-6330 Cham, Switzerland Gewerbestrasse 11.
Responsible
Publisher
Chief Executive Officer, Akadémiai Kiadó
ISSN 0236-5731 (Print)
ISSN 1588-2780 (Online)